Evidence map›Paper›PMID 39055159›Full record

ArticleJACS Au2024

Gonococcal Mimitope Vaccine Candidate Forms a Beta-Hairpin Turn and Binds Hydrophobically to a Therapeutic Monoclonal Antibody.

Peter T Beernink, Cristina Di Carluccio, Roberta Marchetti, Linda Cerofolini, Sara Carillo, Alessandro Cangiano, Nathan Cowieson, Jonathan Bones, Antonio Molinaro, Luigi Paduano and 7 more

Abstract read
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Peter T BeerninkDepartment of Pediatrics, University of California San Francisco, 5700 Martin Luther King Jr. Way, Oakland, California 94609, United States.ORCID https://orcid.org/0000-0001-5734-083X
Cristina Di CarluccioDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.
Roberta MarchettiDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.ORCID https://orcid.org/0000-0002-7173-7099
Linda CerofoliniDepartment of Chemistry, University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.
Sara CarilloNational Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co., Dublin A94 X099, Ireland.
Alessandro CangianoDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.
Nathan CowiesonDiamond Light Source, Didcot, OX11 0DE Oxfordshire, England, United Kingdom.
Jonathan BonesNational Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co., Dublin A94 X099, Ireland.ORCID https://orcid.org/0000-0002-8978-2592
Antonio MolinaroDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.ORCID https://orcid.org/0000-0002-3456-7369
Luigi PaduanoDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.ORCID https://orcid.org/0000-0002-1105-4237
Marco FragaiDepartment of Chemistry, University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.ORCID https://orcid.org/0000-0002-8440-1690
Benjamin P BeerninkDepartment of Pediatrics, University of California San Francisco, 5700 Martin Luther King Jr. Way, Oakland, California 94609, United States.
Sunita GulatiDepartment of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States.
Jutamas ShaughnessyDepartment of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States.
Peter A RiceDepartment of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States.
Sanjay RamDepartment of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States.
Alba SilipoDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.ORCID https://orcid.org/0000-0002-5394-6532

Funding

A novel vaccine against multidrug-resistant gonorrheaR01AI141181 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RAM, SANJAY, RICE, PETER A. · 2019 to 2023
$4.3M
Improved protein-based meningococcal serogroup B vaccinesR01AI134868 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BEERNINK, PETER T. · 2018 to 2022
$3.2M
NIAID NIH HHS R01 AI134868NIAID NIH HHS R01 AI141181
6 · The paper itself

Abstract

The spread of multidrug-resistant strains of

Identifiers

PMID39055159
PMCPMC11267536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.