ReviewJACS Au2024
Exploring the Chemical Space of the Exposome: How Far Have We Gone?
Review in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- In Vitro Bioassay Evidence for Chemical Mixture Propagation from the Environment to Humans.Environmental science & technology · 2026Article
- The Role of ES&T in Advancing Environmental Toxicology and Chemical Risk Assessment: Past, Present, and Future.Environmental science & technology · 2026Review
- Advancing the Discovery of Emerging Contaminants: A Leap in Technology and Data.Environmental science & technology · 2026Review
- Measurable Feature Prediction for Estimating Chemical Space Coverage in LC-ESI-HRMS Nontargeted Analysis.Analytical chemistry · 2026Article
- Silicone-Foam Passive Air Samplers for Combined Target and Nontarget Chemical Profiling and Toxicity Assessment of Airborne Exposomes.Environmental science & technology · 2026Article
- Multimodal 3D-printed passive samplers to monitor, model and prioritiseEnvironmental science. Processes & impacts · 2026Article
- A community-guided approach to monitoring contaminants of emerging concern in freshwater systems using passive samplers.NPJ emerging contaminants · 2026Article
- The Neuroimmunology of Autism.Molecular neurobiology · 2025Review
- Ionization efficiency prediction of electrospray ionization mass spectrometry analytes based on molecular fingerprints and cumulative neutral losses.Journal of cheminformatics · 2025Article
- Large-scale generation of in silico based spectral libraries to annotate dark chemical space features in non-target analysis.Analytical and bioanalytical chemistry · 2025Article
- Development of LC-MS/MS Database Based on 250 Potentially Highly Neuroactive Compounds and Their Metabolites.Metabolites · 2025Article
- A Novel Chemical-Space-Dependent Strategy for Compound Selection in Non-target LC-HRMS Method Development Using Physicochemical and Structural Data.Environmental science & technology letters · 2025Article
- Machine Learning for Enhanced Identification Probability in RPLC/HRMS Nontargeted Workflows.Analytical chemistry · 2025Article
- From Ambition to Action: Navigating Obstacles and Opportunities of "Safe and Sustainable by Design".Environmental science & technology · 2025Review
- Growth vs Diversity: A Time-Evolution Analysis of the Chemical Space.Journal of chemical information and modeling · 2025Article
- Prioritization of Unknown LC-HRMS Features Based on Predicted Toxicity Categories.Environmental science & technology · 2025Article
- Machine Learning-based Classification for the Prioritization of Potentially Hazardous Chemicals with Structural Alerts in Nontarget Screening.Environmental science & technology · 2025Article
- Chemical space as a unifying theme for chemistry.Journal of cheminformatics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Around two-thirds of chronic human disease can not be explained by genetics alone. The Lancet Commission on Pollution and Health estimates that 16% of global premature deaths are linked to pollution. Additionally, it is now thought that humankind has surpassed the safe planetary operating space for introducing human-made chemicals into the Earth System. Direct and indirect exposure to a myriad of chemicals, known and unknown, poses a significant threat to biodiversity and human health, from vaccine efficacy to the rise of antimicrobial resistance as well as autoimmune diseases and mental health disorders. The exposome chemical space remains largely uncharted due to the sheer number of possible chemical structures, estimated at over 10
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.