Evidence map›Paper›PMID 39055008›Full record

ArticleChemical science2024

PYTA: a universal chelator for advancing the theranostic palette of nuclear medicine.

Megan E Simms, Zhiyao Li, Megan M Sibley, Alexander S Ivanov, Caroline M Lara, Timothy C Johnstone, Vilmos Kertesz, Amanda Fears, Frankie D White, Daniel L J Thorek and 1 more

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Stabilities of AcInorganic chemistry · 2026
    Article
  4. Article
  5. Review
  6. Versatile Bifunctional PYTA Derivatives forJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  7. Article
  8. Review
  9. Chelation of [Dalton transactions (Cambridge, England : 2003) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Megan E SimmsChemical Sciences Division, Oak Ridge National Laboratory Oak Ridge TN 37831 USA thielena@ornl.gov.ORCID https://orcid.org/0000-0002-3789-9115
Zhiyao LiDepartment of Radiology, Washington University in St. Louis School of Medicine St. Louis MO 63110 USA thorekd@wustl.edu.
Megan M SibleyChemical Sciences Division, Oak Ridge National Laboratory Oak Ridge TN 37831 USA thielena@ornl.gov.ORCID https://orcid.org/0000-0002-7987-8814
Alexander S IvanovChemical Sciences Division, Oak Ridge National Laboratory Oak Ridge TN 37831 USA thielena@ornl.gov.ORCID https://orcid.org/0000-0002-8193-6673
Caroline M LaraDepartment of Biological Sciences, University of Notre Dame Notre Dame IN 46556 USA.ORCID https://orcid.org/0000-0003-1674-9078
Timothy C JohnstoneDepartment of Chemistry and Biochemistry, University of California Santa Cruz Santa Cruz CA 95064 USA.ORCID https://orcid.org/0000-0003-3615-4530
Vilmos KerteszBiosciences Division, Oak Ridge National Laboratory Oak Ridge TN 37831 USA.ORCID https://orcid.org/0000-0003-0186-5797
Amanda FearsDepartment of Radiology, Washington University in St. Louis School of Medicine St. Louis MO 63110 USA thorekd@wustl.edu.
Frankie D WhiteRadioisotope Science and Technology Division, Oak Ridge National Laboratory Oak Ridge TN 37831 USA whitefd@ornl.gov.ORCID https://orcid.org/0000-0002-8644-1231
Daniel L J ThorekDepartment of Radiology, Washington University in St. Louis School of Medicine St. Louis MO 63110 USA thorekd@wustl.edu.ORCID https://orcid.org/0000-0003-2437-1239
Nikki A ThieleChemical Sciences Division, Oak Ridge National Laboratory Oak Ridge TN 37831 USA thielena@ornl.gov.ORCID https://orcid.org/0000-0003-3301-0849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To clinically advance the growing arsenal of radiometals available to image and treat cancer, chelators with versatile binding properties are needed. Herein, we evaluated the ability of the py

Identifiers

PMID39055008
PMCPMC11268510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.