Evidence map›Paper›PMID 39054949›Full record

ArticleInternational journal of aging & human development2024

Intersections of Modifiable Risks: Loneliness is Associated with Poor Subjective Sleep Quality in Older Women at Risk for Alzheimer's Disease.

Madina Danish, Melanie A Dratva, Kitty K Lui, Nadine Heyworth, Xin Wang, Atul Malhotra, Sheri J Hartman, Ellen E Lee, Erin E Sundermann, Sarah J Banks

Abstract read
In one paragraph

Article in International journal of aging & human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Madina DanishMADURA ADAR Program, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-3161-2945
Melanie A DratvaDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Kitty K LuiJoint Doctoral Program in Clinical Psychology, SDSU/UC San Diego, San Diego, CA, USA.
Nadine HeyworthDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Xin WangDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Atul MalhotraDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Sheri J HartmanDepartment of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA.
Ellen E LeeDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Erin E SundermannDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Sarah J BanksDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Mark W Bondi · 2019 to 2026
$34.9M
Biological and lifestyle factors contributing to Tau in women at risk for Alzheimer's disease.R01AG080663 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SARAH BANKS, Erin elizabeth Sundermann · 2023 to 2026
$4.2M
Is Obstructive Sleep Apnea Important in the Development of Alzheimer's DiseaseR01AG063925 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2020 to 2024
$3.7M
Underlying mechanisms of obesity-induced obstructive sleep apneaR01HL148436 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2020 to 2026
$3.4M
Sleep Apnea Endophenotypes: One Size Does Not Fit AllR01HL154926 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2021 to 2025
$3.3M
The cardiovascular consequences of sleep apnea plus COPD (Overlap syndrome)R01HL166485 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2023 to 2026
$3.1M
VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19R01HL157985 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, NEMATI, SHAMIM · 2022 to 2025
$2.9M
The MADURA Program: Mentorship for Advancing Diversity in Undergraduate Research on AgingR25AG066594 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Steven Dyal Edland · 2020 to 2026
$2.5M
Developing a Diverse Next Generation of Leaders in Respiratory ScienceT32HL166127 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Laura Elise Crotty Alexander, Atul Malhotra · 2023 to 2026
$1.6M
NHLBI NIH HHS R01 HL148436NHLBI NIH HHS R01 HL154926NHLBI NIH HHS R01 HL157985NHLBI NIH HHS R01 HL166485NHLBI NIH HHS T32 HL166127NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG063925NIA NIH HHS R01 AG080663NIA NIH HHS R25 AG066594
6 · The paper itself

Abstract

We examined the relationship between subjective and objective sleep outcomes and loneliness in older women at risk for Alzheimer's disease (AD). Our sample consisted of 39 participants (aged 65+) with mild cognitive deficits who completed the UCLA Loneliness Scale, the Pittsburgh Sleep Quality Index (PSQI), and an at home sleep test, to determine presence of obstructive sleep apnea. Based on sleep quality scores, individuals categorized as "poor sleepers" had significantly higher loneliness scores than "good sleepers." However, total loneliness scores did not significantly differ between groups with or without sleep apnea. We found that higher loneliness was significantly associated to lower habitual sleep efficiency and sleep duration and was also influenced by use of sleep medication. Our findings suggest that increased loneliness relates to worse subjective sleep quality, but not to sleep apnea. These findings suggest that combined interventions targeting loneliness and sleep quality may be important for older women.

Indexed as

Alzheimer DiseaseCognitive DysfunctionLonelinessSleep QualityAgedAged, 80 and overFemaleHumansRisk FactorsSleep Apnea, ObstructiveSleep Wake DisordersADARAlzheimer's diseaseslonelinessmodifiable risk factorssleep quality

Identifiers

PMID39054949
PMCPMC11490093

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.