Evidence map›Paper›PMID 39054725›Full record

ArticlePediatric blood & cancer2024

Standardizing the evaluation and management of iron deficiency anemia secondary to heavy menstrual bleeding in the emergency department.

Josaura Fernandez Sanchez, Luisanna M Sánchez, Sarah S Kappa, Cecile L Karsenty, Madeleine O'Keefe, Meghan Shekar, Leander D Timothy, Chelsea B Vrana, Gladstone Airewele, YoungNa Lee-Kim and 3 more

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Josaura Fernandez SanchezDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Luisanna M SánchezDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-6506-4772
Sarah S KappaDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Cecile L KarsentyDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0001-8901-0261
Madeleine O'KeefeDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Meghan ShekarDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Leander D TimothyDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Chelsea B VranaDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Gladstone AireweleDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
YoungNa Lee-KimDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
M Fatih OkcuDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.
Clay T CohenDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0001-6819-4049
Jacquelyn M PowersDepartment of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA.

Funding

PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAMK12CA090433 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CARL E ALLEN, Donald W. Parsons · 2002 to 2026
$18.5M
The PreVAIL-kIds Common ProtocolR33HD105593 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI ALLEN, CARL E, ANNAPRAGADA, ANANTH V · 2023 to 2023
$6.3M
NCI NIH HHS K12 CA090433NICHD NIH HHS R33 HD105593
6 · The paper itself

Abstract

backgroundComprehensive guidelines for the management of iron deficiency anemia (IDA) in adolescents with heavy menstrual bleeding (HMB) presenting to the emergency department (ED) are lacking, leading to variability in care. We aimed to standardize the evaluation and management of these patients through the development and implementation of an evidence-based algorithm using quality improvement methodology.

methodsBaseline data of the target population identified variability across four key measures of clinical management: therapy choice and administration, laboratory evaluation, hematology service consultation, and patient disposition. Literature review and consensus from pediatric hematology and gynecology providers informed a draft algorithm that was refined in an iterative multidisciplinary process. From December 2022 to July 2023, we aimed to achieve a 25% relative increase in patients to receive optimal management per the algorithm, while using sequential Plan-Do-Study-Act (PDSA) cycles. Process measures focusing on provider documentation and balancing measures, such as ED length of stay, were assessed concurrently.

resultsForty-nine patients were evaluated during four PDSA cycles. Improvement of ≥40% above baseline regarding recommended therapy administration was achieved across four PDSA cycles. Adherence to recommended therapy choice improved from 57% (baseline) to 100%, minimal laboratory evaluation from 14% to 83%, hematology consultation from 36% to 100%, and appropriate disposition from 71% to 100%. ED length of stay remained stable.

conclusionImplementation of a standardized algorithm for management of IDA secondary to HMB in adolescents in the ED increased adherence to evidence-based patient care.

Indexed as

AlgorithmsAnemia, Iron-DeficiencyEmergency Service, HospitalMenorrhagiaAdolescentDisease ManagementFemaleHumansPractice Guidelines as TopicPrognosisQuality Improvementheavy menstrual bleedingiron deficiency anemia

Identifiers

PMID39054725
PMCPMC12051210

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.