Evidence map›Paper›PMID 39054673›Full record

ArticleBiophysical journal2024

Interior pH-sensing residue of human voltage-gated proton channel H

Mingzhe Shen, Yandong Huang, Zhitao Cai, Vladimir V Cherny, Thomas E DeCoursey, Jana Shen

Abstract read
In one paragraph

Article in Biophysical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Fluctuating hydrogen-bond network of the Hv1 ion channel.Computational and structural biotechnology journal · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingzhe ShenDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland.
Yandong HuangCollege of Computer Engineering, Jimei University, Xiamen, Fujian Province, China. Electronic address: yandonghuang@jmu.edu.cn.
Zhitao CaiCollege of Computer Engineering, Jimei University, Xiamen, Fujian Province, China.
Vladimir V ChernyDepartment of Physiology & Biophysics, Rush University Medical Center, Chicago, Illinois.
Thomas E DeCourseyDepartment of Physiology & Biophysics, Rush University Medical Center, Chicago, Illinois.
Jana ShenDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland. Electronic address: jana.shen@rx.umaryland.edu.

Funding

Molecular mechanisms of proton-coupled dynamic processes in biologyR35GM148261 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Jana Shen · 2023 to 2026
$1.5M
Control Mechanisms of Human Voltage Gated Proton Channels, hHv1R35GM151963 · NIGMS · RUSH UNIVERSITY MEDICAL CENTER · PI THOMAS E DECOURSEY · 2024 to 2026
$1.3M
NIGMS NIH HHS R35 GM148261NIGMS NIH HHS R35 GM151963
6 · The paper itself

Abstract

The molecular mechanisms governing the human voltage-gated proton channel hH

Indexed as

HistidineIon ChannelsMolecular Dynamics SimulationHumansHydrogen-Ion ConcentrationIon Channel GatingProtonsHistidineHVCN1 protein, humanIon ChannelsProtons

Identifiers

PMID39054673
PMCPMC11700365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.