Evidence map›Paper›PMID 39054511›Full record

ArticleCritical care (London, England)2024

Changes in quality of life 1 year after intensive care: a multicenter prospective cohort of ICU survivors.

Lucy L Porter, Koen S Simons, Stijn Corsten, Brigitte Westerhof, Thijs C D Rettig, Esther Ewalds, Inge Janssen, Crétien Jacobs, Susanne van Santen, Arjen J C Slooter and 4 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Critical care (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03246334 (MONITOR-IC), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03246334 recruitingnot on this map

MONITOR-IC: a Mixed Methods Multicenter Prospective Open Cohort Study Determining and Improving Long-term Outcomes of ICU Survivors

TypeobservationalSponsorRadboud University Medical CenterRan2016 to 2050Enrolled50,000ConditionsPost-Intensive Care Syndrome (PICS)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Observational
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  5. Observational
  6. Early health economic assessment of eLiActa neuropsychiatrica · 2026
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  14. Getting valuable and valid insight in life after ICU: evaluating the representativeness of a large cohort of ICU survivors.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lucy L PorterDepartment of Intensive Care, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Koen S SimonsDepartment of Intensive Care, Jeroen Bosch Hospital, 's Hertogenbosch, The Netherlands.
Stijn CorstenDepartment of Intensive Care, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Brigitte WesterhofDepartment of Intensive Care, Rijnstate Hospital, Arnhem, The Netherlands.
Thijs C D RettigDepartment of Anesthesiology, Intensive Care and Pain Medicine, Amphia Hospital, Breda, The Netherlands.
Esther EwaldsDepartment of Intensive Care, Bernhoven Hospital, Uden, The Netherlands.
Inge JanssenDepartment of Intensive Care, Maas Hospital Pantein, Boxmeer, The Netherlands.
Crétien JacobsDepartment of Intensive Care, Elkerliek Hospital, Helmond, The Netherlands.
Susanne van SantenDepartment of Intensive Care, Maastricht University Medical Center, Maastricht, The Netherlands.
Arjen J C SlooterDepartments of Psychiatry and Intensive Care Medicine, and UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Margaretha C E van der WoudeZuyderland Medical Center, Department of Intensive Care, Heerlen, The Netherlands.
Johannes G van der HoevenDepartment of Intensive Care, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Marieke ZegersDepartment of Intensive Care, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Mark van den BoogaardDepartment of Intensive Care, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands. Mark.vandenBoogaard@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith survival rates of critical illness increasing, quality of life measures are becoming an important outcome of ICU treatment. Therefore, to study the impact of critical illness on quality of life, we explored quality of life before and 1 year after ICU admission in different subgroups of ICU survivors.

methodsData from an ongoing prospective multicenter cohort study, the MONITOR-IC, were used. Patients admitted to the ICU in one of eleven participating hospitals between July 2016 and June 2021 were included. Outcome was defined as change in quality of life, measured using the EuroQol five-dimensional (EQ-5D-5L) questionnaire, and calculated by subtracting the EQ-5D-5L score 1 day before hospital admission from the EQ-5D-5L score 1 year post-ICU. Based on the minimal clinically important difference, a change in quality of life was defined as a change in EQ-5D-5L score of ≥ 0.08. Subgroups of patients were based on admission diagnosis.

resultsA total of 3913 (50.6%) included patients completed both baseline and follow-up questionnaires. 1 year post-ICU, patients admitted after a cerebrovascular accident, intracerebral hemorrhage, or (neuro)trauma, on average experienced a significant decrease in quality of life. Conversely, 11 other subgroups of ICU survivors reported improvements in quality of life. The largest average increase in quality of life was seen in patients admitted due to respiratory disease (mean 0.17, SD 0.38), whereas the largest average decrease was observed in trauma patients (mean -0.13, SD 0.28). However, in each of the studied 22 subgroups there were survivors who reported a significant increase in QoL and survivors who reported a significant decrease in QoL.

conclusionsThis large prospective multicenter cohort study demonstrated the diversity in long-term quality of life between, and even within, subgroups of ICU survivors. These findings emphasize the need for personalized information and post-ICU care.

trial registrationThe MONITOR-IC study was registered at ClinicalTrials.gov: NCT03246334 on August 2nd 2017.

Indexed as

Intensive Care UnitsQuality of LifeSurvivorsAdultAgedCohort StudiesCritical CareCritical IllnessFemaleHumansMaleMiddle AgedProspective StudiesSurveys and QuestionnairesCritical care outcomesPatient-reported outcome measuresPrognosisQuality of life

Identifiers

PMID39054511
PMCPMC11271204

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.