Evidence map›Paper›PMID 39054410›Full record

ArticleBMC cardiovascular disorders2024

Predicting high-risk pre-capillary pulmonary hypertension: an echocardiographic multiparameter scoring index.

Yanan Zhai, Aili Li, Xincao Tao, Qian Gao, Wanmu Xie, Yu Zhang, Aihong Chen, Chi Wang, Jieping Lei, Shangwei Ding and 2 more

Abstract readValidation Study
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Yanan ZhaiDepartment of Cardiology, China-Japan Friendship Hospital, No. 2, East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Aili LiDepartment of Cardiology, China-Japan Friendship Hospital, No. 2, East Yinghua Road, Chaoyang District, Beijing, 100029, China. echoaili@163.com.
Xincao TaoInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Qian GaoInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Wanmu XieInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Yu ZhangDepartment of Cardiology, China-Japan Friendship Hospital, No. 2, East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Aihong ChenDepartment of Cardiology, China-Japan Friendship Hospital, No. 2, East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Chi WangHeart Health Research Center, Beijing, China.
Jieping LeiInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Shangwei DingDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Yantong CaiDepartment of Ultrasound, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Zhenguo ZhaiInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Funding

Capital's Funds for Health Improvement and Research 2020-2-4063Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (CIFMS) 2021-I2M-1-049
6 · The paper itself

Abstract

backgroundThe risk stratification of pulmonary arterial hypertension proposed by the European Society of Cardiology /European Respiratory Society guidelines in 2015 and 2022 included two to three echocardiographic indicators. However, the specific value of echocardiography in risk stratification of pre-capillary pulmonary hypertension (pcPH) has not been efficiently demonstrated. Given the complex geometry of the right ventricular (RV) and influencing factors of echocardiographic parameter, there is no single echocardiographic parameter that reliably informs about PH status. We hypothesize that a multi-parameter comprehensive index can more accurately evaluate the severity of the pcPH. The purpose of this study was to develop and validate an echocardiographic risk score model to better assist clinical identifying high risk of pcPH during initial diagnosis and follow-up.

methodsWe studied 197 consecutive patients with pcPH. A multivariable echocardiographic model was constructed to predict the high risk of pcPH in the training set. Points were assigned to significant risk factors in the final model based on β-coefficients. We validated the model internally and externally.

resultsThe echocardiographic score was constructed by multivariable logistic regression, which showed that pericardial effusion, right atrial (RA) area, RV outflow tract proximal diameter (RVOT-Prox), the velocity time integral of the right ventricular outflow tract (TVI

conclusionsThe echocardiographic risk score using five echocardiographic parameters could be comprehensive and useful to predict the high risk of pcPH for initial assessment and follow-up.

Indexed as

Predictive Value of TestsVentricular Function, RightAdultAgedArterial PressureDecision Support TechniquesEchocardiography, DopplerFemaleHumansHypertension, PulmonaryMaleMiddle AgedPrognosisPulmonary Arterial HypertensionPulmonary ArteryReproducibility of ResultsEchocardiographyPulmonary hypertensionRight ventricule, Scoring index, risk stratification

Identifiers

PMID39054410
PMCPMC11271058

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