Evidence map›Paper›PMID 39053935›Full record

Trial reportJournal of neurointerventional surgery2025

Detection of early neurological deterioration using a quantitative electroencephalography system in patients with large vessel occlusion stroke after endovascular treatment.

Yujia Yan, Xingwei An, Yuxiang Ma, Zeliang Jiang, Yang Di, Tingting Li, Honglin Wang, Hecheng Ren, Lin Ma, Bin Luo and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yujia YanTianjin Key Laboratory of Brain Science and Neuroengineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, People's Republic of China.ORCID http://orcid.org/0000-0002-7656-8634
Xingwei AnTianjin Key Laboratory of Brain Science and Neuroengineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, People's Republic of China.
Yuxiang MaDepartment of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, People's Republic of China.
Zeliang JiangDepartment of Psychology, Hebei Normal University, Shijiazhuang, Hebei, People's Republic of China.
Yang DiTianjin Key Laboratory of Brain Science and Neuroengineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, People's Republic of China.
Tingting LiTianjin Key Laboratory of Brain Science and Neuroengineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, People's Republic of China.
Honglin WangTianjin Key Laboratory of Brain Science and Neuroengineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, People's Republic of China.
Hecheng RenDepartment of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, People's Republic of China.
Lin MaDepartment of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, People's Republic of China.
Bin LuoDepartment of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, People's Republic of China.
Ying HuangDepartment of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, People's Republic of China yinghuang0000@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly neurological deterioration (END) is a serious complication in patients with large vessel occlusion (LVO) stroke. However, modalities to monitor neurological function after endovascular treatment (EVT) are lacking. This study aimed to evaluate the diagnostic accuracy of a quantitative electroencephalography (qEEG) system for detecting END.

methodsIn this prospective, nested case-control study, we included 47 patients with anterior circulation LVO stroke and 34 healthy adults from different clinical centers in Tianjin, China, from May 2023 to January 2024. Patients with stroke underwent EEG at admission and after EVT. The diagnostic accuracy of qEEG features for END was evaluated by receiver operating characteristic curve analysis, and the feasibility was evaluated by the percentage of artifact-free data and device-related adverse events.

results14 patients with stroke had END (29.8%, 95% CI 16.2% to 43.4%), with most developed within 12 hours of recanalization (n=11). qEEG features showed significant correlations with National Institutes of Health Stroke Scale score and infarct volume. After matching, 13 patients with END and 26 controls were included in the diagnostic analysis. Relative alpha power demonstrated the highest diagnostic accuracy for the affected and unaffected hemispheres. The optimal electrode positions were FC3/4 in the unaffected hemisphere, and F7/8 and C3/4 in the affected hemisphere. No device-related adverse events were reported.

conclusionThe qEEG system exhibits a high diagnostic accuracy for END and may be a promising tool for monitoring neurological function. The identification of optimal electrode positions may enhance device convenience. CLINICAL

trial registrationChiCTR 2300070829.

Indexed as

ElectroencephalographyEndovascular ProceduresIschemic StrokeStrokeAgedCase-Control StudiesFemaleHumansMaleMiddle AgedProspective StudiesEEGStrokeThrombectomy

Identifiers

PMID39053935
PMCPMC12322402

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.