Evidence map›Paper›PMID 39053144›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Thrombotic Prediction Model Based on Epigenetic Regulator Mutations in Essential Thrombocythemia Patients Using Survival Analysis in Recurrent Events.

Pirun Saelue, Patuma Sinthujaroen, Supaporn Suwiwat, Paramee Thongsuksai

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Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pirun SaelueHematology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.
Patuma SinthujaroenDepartment of Pathology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.
Supaporn SuwiwatDepartment of Pathology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.
Paramee ThongsuksaiDepartment of Pathology, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.ORCID 0000-0003-4226-7988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEssential thrombocythemia (ET) involves the proliferation of megakaryocytes and platelets and is associated with an increased risk of thrombosis. We aimed to evaluate thrombotic risks in patients with epigenetic regulator mutations and generate a model to predict thrombosis in ET. MATERIALS AND

methodsThis cohort study enrolled patients aged > 15 years diagnosed with ET at the Songklanakarind Hospital between January 2002 and December 2019. Twenty-five targeted gene mutations, including somatic driver mutations (

resultsNinety-six patients were enrolled with a median follow-up of 6.91 years. Of these, 15 patients experienced 17 arterial thrombotic events in total. Patients with

conclusionsThe PWP gap-time model was a good predictive model for thrombotic risk in patients with ET.

Indexed as

MutationThrombocythemia, EssentialThrombosisAdultAgedCohort StudiesEpigenesis, GeneticFemaleHumansMaleMiddle AgedRecurrenceSurvival AnalysisYoung Adultepigenetic mutationessential thrombocythemiaprediction modelsurvival analysis in recurrent eventthrombosis

Identifiers

PMID39053144
PMCPMC11282546

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.