Evidence map›Paper›PMID 39052177›Full record

ArticleBioresources and bioprocessing2024

Reparative effects of Schizophyllum commune oat bran fermentation broth on UVB-induced skin inflammation via the JAK/STAT pathway.

Zixin Song, Jiman Geng, Dongdong Wang, Jiaxuan Fang, Ziwen Wang, Changtao Wang, Meng Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioresources and bioprocessing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Exploring the Active Constituents ofAntioxidants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zixin Song *College of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Jiman Geng *College of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Dongdong WangCollege of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China. wdd@btbu.edu.cn.ORCID http://orcid.org/0000-0001-8452-0158
Jiaxuan FangCollege of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Ziwen WangCollege of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Changtao WangCollege of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China. wangct@th.btbu.edu.cn.
Meng LiCollege of Light Industry Science and Engineering, Beijing Technology & Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.

Funding

The State Administration for Market Regulation Science and Technology Plan Project 2022MK192
6 · The paper itself

Abstract

Human immortal keratinocyte cells (HaCaT) are induced with UVB to establish an injury model. This model is utilized to investigate whether oat bran fermentation broth (OBF) has a reparative effect on skin inflammation and damage to the skin barrier caused by UVB irradiation. The results show that compared with unfermented oat bran (OB), OBF exhibits higher structural homogeneity, increased molecular weight size, active substances content, and in vitro antioxidant activity. OBF has a scavenging effect on excess reactive oxygen species (ROS) and increases the intracellular levels of antioxidant enzymes. It was found that OBF has a stronger inhibitory effect on the release of inflammatory factors than OB. It increases the synthesis of AQP3 and FLG proteins while decreasing the secretion of KLK-7. OBF can inhibit the transcription level of inflammatory factors by suppressing the JAK/STAT signaling pathway. Safety experiments demonstrate that OBF has a high safety profile.

Indexed as

JAK/STAT pathwayOat branSchizophyllum communeSkin inflammation

Identifiers

PMID39052177
PMCPMC11272765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.