Evidence map›Paper›PMID 39052061›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2024

The challenge of antimicrobial resistance (AMR): current status and future prospects.

Francesco Ferrara, Tommaso Castagna, Beatrice Pantolini, Maria Chiara Campanardi, Martina Roperti, Alessandra Grotto, Martina Fattori, Lucia Dal Maso, Federica Carrara, Giulia Zambarbieri and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  4. Article
  5. Review
  6. Genomic Surveillance of ESBL-ProducingPathogens (Basel, Switzerland) · 2026
    Article
  7. Article
  8. ZnO@TiOMaterials (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Discovery of new bioactive secondary metabolites from the stem bark of oroxylum indicum: isolation, structural identification, antimicrobial and cytotoxicity assessment.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francesco FerraraPharmaceutical Department, Asl Napoli 3 Sud, Dell'amicizia Street 72, 80035, Nola, Naples, Italy. f.ferrara@aslnapoli3sud.it.ORCID http://orcid.org/0000-0001-9298-6783
Tommaso CastagnaPharmacy Unit, ASST Di Lecco, Dell'Eremo Street 9/11, 23900, Lecco, Italy.ORCID http://orcid.org/0009-0004-8985-0323
Beatrice PantoliniUniversity of Milan, Festa del Perdono Street 7, 20122, Milan, Italy.ORCID http://orcid.org/0009-0000-3636-0225
Maria Chiara CampanardiFondazione IRCCS Istituto Nazionale Tumori, Giacomo Venezian Street 1, 20122, Milan, Italy.ORCID http://orcid.org/0009-0009-4372-2082
Martina RopertiIRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, 20159, Milan, Italy.ORCID http://orcid.org/0009-0007-9326-5129
Alessandra GrottoUniversity of Milan, Festa del Perdono Street 7, 20122, Milan, Italy.ORCID http://orcid.org/0009-0005-8935-8694
Martina FattoriIstituto Europeo Di Oncologia, Ripamonti Street 435, 20122, Milan, Italy.ORCID http://orcid.org/0009-0001-7027-8257
Lucia Dal MasoPharmaceutical Department, ASST Santi Paolo E Carlo, Antonio Rudinì Street 8, 20159, Milan, Italy.ORCID http://orcid.org/0009-0006-2313-3895
Federica CarraraPharmaceutical Department, Humanitas Gavazzeni, Mauro Gavazzeni Street 21, 24125, Bergamo, BG, Italy.ORCID http://orcid.org/0000-0002-8895-3425
Giulia ZambarbieriPharmaceutical Department, Humanitas Gavazzeni, Mauro Gavazzeni Street 21, 24125, Bergamo, BG, Italy.ORCID http://orcid.org/0009-0008-2449-5497
Andrea ZoviMinistry of Health, Viale Giorgio Ribotta 5, 00144, Rome, Italy.ORCID http://orcid.org/0000-0002-6528-2171
Maurizio CapuozzoPharmaceutical Department, Asl Napoli 3 Sud, Dell'amicizia Street 72, 80035, Nola, Naples, Italy.ORCID http://orcid.org/0000-0001-9488-6057
Roberto LangellaItalian Society of Hospital Pharmacy (SIFO), SIFO Secretariat of the Lombardy Region, Via Carlo Farini, 81, 20159, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) represents a critical global threat, compromising the effectiveness of antibacterial drugs as bacteria adapt and survive exposure to many classes of these drugs. This phenomenon is primarily fueled by the widespread overuse and misuse of antibacterial drugs, exerting selective pressure on bacteria and promoting the emergence of multi-resistant strains. AMR poses a top-priority challenge to public health due to its widespread epidemiological and economic implications, exacerbated not only by the diminishing effectiveness of currently available antimicrobial agents but also by the limited development of genuinely effective new molecules. In addressing this issue, our research aimed to examine the scientific literature narrating the Italian situation in the common European context of combating AMR. We sought to delineate the current state of AMR and explore future prospects through an analysis of strategies to counter antibacterial drug resistance. Adopting the "One Health" model, our objective was to comprehensively engage diverse sectors, integrate various disciplines, and propose programs, policies, and regulations. This narrative review, based on PubMed research related to antibiotic resistance, emphasizes the urgent need for a coordinated and proactive approach at both national and European levels to mitigate the impact of AMR and pave the way for effective strategies to counter this global health challenge.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialAnimalsBacteriaBacterial InfectionsHumansItalyAnti-Bacterial AgentsAntimicrobial resistanceBacteriaGlobal healthStrategiesTreatments

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.