Evidence map›Paper›PMID 39051344›Full record

ArticleJournal of xenobiotics2024

Temporal Analysis of Pharmaceuticals as Emerging Contaminants in Surface Water and Wastewater Samples: A Case Study.

Paula Paíga, Luísa Correia-Sá, Manuela Correia, Sónia Figueiredo, Joana Vieira, Sandra Jorge, Jaime Gabriel Silva, Cristina Delerue-Matos

Abstract read
In one paragraph

Article in Journal of xenobiotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paula PaígaREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, Portugal.ORCID 0000-0002-9593-1355
Luísa Correia-SáREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, Portugal.
Manuela CorreiaREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, Portugal.ORCID 0000-0002-3014-5089
Sónia FigueiredoREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, Portugal.ORCID 0000-0001-8548-2528
Joana VieiraÁguas do Centro Litoral, SA, Grupo Águas de Portugal, ETA da Boavista, Avenida Dr. Luís Albuquerque, 3030-410 Coimbra, Portugal.
Sandra JorgeÁguas do Centro Litoral, SA, Grupo Águas de Portugal, ETA da Boavista, Avenida Dr. Luís Albuquerque, 3030-410 Coimbra, Portugal.
Jaime Gabriel SilvaÁguas do Douro e Paiva, SA, Grupo Águas de Portugal, Rua de Vilar, 235 5°, 4050-626 Porto, Portugal.
Cristina Delerue-MatosREQUIMTE/LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, Portugal.ORCID 0000-0002-3924-776X

Funding

Fundação para a Ciência e a Tecnologia (FCT) BiodivRestore Joint Call 2020-2021 - European Union's Horizon 2020 research and innovation programme 101003777Fundação para a Ciência e Tecnologia LA/P/0008/2020Fundação para a Ciência e Tecnologia MTS/SAS/0077/2020Fundação para a Ciência e Tecnologia PTDC/EAM-AMB/2023/2021Fundação para a Ciência e Tecnologia PTDC/QUI-QAN/3899/2021Fundação para a Ciência e Tecnologia UIDB/50006/2020Fundação para a Ciência e Tecnologia UIDP/50006/2020Ibero-American Program on Science and Technology (CYTED) & European Cooperation in Science and Technology (COST) P223RT0141/ENOTTA-CA21147
6 · The paper itself

Abstract

Pharmaceuticals in the environment are a global concern, with studies in all continents highlighting their widespread occurrence and potential ecological impacts, revealing their presence, fate, and associated risks in aquatic ecosystems. Despite typically occurring at low concentrations (ranging from ng/L to µg/L), advancements in analytical methods and more sensitive equipment have enabled the detection of a higher number of pharmaceuticals. In this study, surface and wastewater samples were extracted using solid phase extraction and analyzed using ultra-high-performance liquid chromatography with tandem mass spectrometry. Among the therapeutic classes investigated, nonsteroidal anti-inflammatory drugs/analgesics, antibiotics, and psychiatric drugs showed a higher number of detected pharmaceuticals. Concentrations ranged from below method detection limit (<MDL) to 3.20 µg/L (caffeine) and <MDL to 639 µg/L (hydroxyibuprofen) in 2018, and from <MDL to 0.848 µg/L (diclofenac) and <MDL to 53.0 µg/L (caffeine) in 2019 for river water and wastewater samples. Temporal analysis showed an increase in the sum of pharmaceutical concentrations over the study years, highlighting the importance of monitoring pharmaceuticals in the environment and their potential accumulation over time.

Indexed as

liquid chromatographymass spectrometryovertime analysispharmaceuticalspublic healthsurface and wastewater samples

Identifiers

PMID39051344
PMCPMC11270430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.