Evidence map›Paper›PMID 39051326›Full record

ArticleAntibodies (Basel, Switzerland)2024

Development, Optimization and Evaluation of a Sensitive Enzyme-Linked Immunosorbent Assay (ELISA) Prototype for Detection of Chicken-Based IgY Polyclonal Antibodies against Toxins of

Stephen Wilson Kpordze, Gideon Mutie Kikuvi, James Hungo Kimotho, Victor Atunga Mobegi

Abstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephen Wilson KpordzeDepartment of Molecular Biology and Biotechnology, Pan African University Institute for Basic Sciences, Technology and Innovation (PAUSTI), JKUAT-Juja Campus, Nairobi 62000-00200, Kenya.ORCID 0000-0002-5694-9018
Gideon Mutie KikuviDepartment of Environmental Health and Disease Control, Jomo Kenyatta University of Agriculture and Technology, JKUAT-Juja Campus, Nairobi 62000-00200, Kenya.
James Hungo KimothoKenya Medical Research Institute, Off Raila Odinga Way, Nairobi 54840-00200, Kenya.
Victor Atunga MobegiDepartment of Biochemistry, University of Nairobi, Chiromo Campus, Nairobi 30197-00100, Kenya.

Funding

African Union Commission Scholarship
6 · The paper itself

Abstract

Life-threatening medical issues can result from snakebite, and hence this is a public health concern. In many tropical and subtropical nations such as Kenya, where a wide variety of poisonous snakes are prevalent, diagnosis of snakebite in health facilities is imperative. Different antivenoms are needed to treat the venom of different snake species. Nonetheless, it might be difficult for medical professionals to identify the exact snake species that envenomated a patient due to the similarities of several snake envenomations' clinical symptoms. Therefore, the necessity for an assay or technique for identifying venomous species is critical. The current study sought to develop a sensitive ELISA prototype for the detection of

Indexed as

antivenomschicken-based IgYD. polylepis venomELISAoptimization

Identifiers

PMID39051326
PMCPMC11270286

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.