Evidence map›Paper›PMID 39051302›Full record

ArticleClinics and practice2024

Assessment of 2'-Fucosyllactose and Lacto-N-Neotetraose Solution as an Irrigant in

Francesco Puleio, Rosario Pirri, Vincenzo Tosco, Angelo Sergio Lizio, Paola Tripodi, Isabella La Spina, Vincenza La Fauci, Raffaele Squeri

Abstract read
In one paragraph

Article in Clinics and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco PuleioDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.ORCID 0000-0003-2819-7266
Rosario PirriDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.
Vincenzo ToscoDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-3378-3844
Angelo Sergio LizioDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.
Paola TripodiDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.
Isabella La SpinaDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.
Vincenza La FauciDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.ORCID 0000-0002-5038-8811
Raffaele SqueriDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, 98100 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the lack of an ideal endodontic irrigant on the market, this study evaluates the antimicrobial potential of a formulated solution of 2'-fucosyllactose and lacto-N-neotetraose against

methods32 single-rooted teeth extracted for periodontal reasons were infected with

resultsthe analysis of the results obtained from the comparison of groups irrigated with sodium hypochlorite or a solution of 2'-fucosyllactose and lacto-N-neotetraose demonstrates that the case solution has no bactericidal effect against

conclusionsthe HMOs used in this study do not have a bactericidal effect on

Indexed as

endodontic irrigationendodontic treatmentEnterococcus faecalishuman milk oligosaccharides

Identifiers

PMID39051302
PMCPMC11270313

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.