Evidence map›Paper›PMID 39051189›Full record

ArticleAdvances in respiratory medicine2024

Physically Active Lifestyle Attenuates Impairments on Lung Function and Mechanics in Hypertensive Older Adults.

Maysa Alves Rodrigues Brandao-Rangel, Boris Brill, Edilson de Souza Carvalho, Dobroslav Melamed, Renilson Moraes-Ferreira, Anamei Silva-Reis, Patricia Sardinha Leonardo, Claudio Ricardo Frison, Kátia De Angelis, Rodolfo P Vieira

Abstract read
In one paragraph

Article in Advances in respiratory medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maysa Alves Rodrigues Brandao-RangelFederal University of Sao Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Avenida Ana Costa 95, Santos 11060-001, SP, Brazil.ORCID 0000-0002-9284-8695
Boris BrillLeniado Medical Center, Divrei Khayim St 16, Nethanya 4244916, Israel.
Edilson de Souza CarvalhoEvangelical University of Goias (Unievangelica), Post-graduation Program in Humam Movement and Rehabilitation and in Pharmaceutical Sciences, Pharmacology and Therapeutics, Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Dobroslav MelamedLibiPharm, Department of Research and Development, Derech Ben Gurion 70, Rehovot 7639461, Israel.
Renilson Moraes-FerreiraFederal University of Sao Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Avenida Ana Costa 95, Santos 11060-001, SP, Brazil.
Anamei Silva-ReisEvangelical University of Goias (Unievangelica), Post-graduation Program in Humam Movement and Rehabilitation and in Pharmaceutical Sciences, Pharmacology and Therapeutics, Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Patricia Sardinha LeonardoEvangelical University of Goias (Unievangelica), Post-graduation Program in Humam Movement and Rehabilitation and in Pharmaceutical Sciences, Pharmacology and Therapeutics, Avenida Universitária Km 3,5, Anápolis 75083-515, GO, Brazil.
Claudio Ricardo FrisonFederal University of Sao Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Avenida Ana Costa 95, Santos 11060-001, SP, Brazil.
Kátia De AngelisFederal University of Sao Paulo (UNIFESP), Department of Physiology, Rua Botucatu 862, São Paulo 04023-901, SP, Brazil.
Rodolfo P VieiraFederal University of Sao Paulo (UNIFESP), Post-graduation Program in Sciences of Human Movement and Rehabilitation, Avenida Ana Costa 95, Santos 11060-001, SP, Brazil.ORCID 0000-0001-6379-1143

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) #2012/15165-2. MARBR holds a PhD fellowship from FAPESP (2019/05739-0). RMF holds a MSc fellowship from FAPESP (2019/11008-9). ASR holds a MSc fellowship from FAPESP (2019/11244-4).
6 · The paper itself

Abstract

aimPhysical activity attenuates hypertension in older adults, but its impact on pulmonary function and mechanics in hypertensive older adults is unknown. The study seeks to understand whether a physically active lifestyle can improve respiratory capacity, the mechanical efficiency of the lungs, and, consequently, the quality of life of these individuals, comparing data between groups of active and sedentary hypertensive older adults.

methodsThis is a cross-sectional study. We evaluated 731 older adults, stratified into two initial groups: hypertensive older adults (HE; n = 445) and non-hypertensive older adults (NHE; n = 286). For a secondary analysis, we used the International Physical Activity Questionnaire to sub-stratify HE and NHE into four groups: physically inactive hypertensive (PIH; n = 182), active hypertensive (AH; n = 110), physically inactive non-hypertensive (PINH; n = 104), and active non-hypertensive (ANH; n = 65). Lung function was measured by spirometry, and lung mechanics were assessed by impulse oscillometry.

resultsHypertensive older adults presented reduced lung function compared to non-hypertensive older adults, and physical inactivity accentuated this decline. Regarding pulmonary mechanics, hypertensive older adults had higher resistance of the entire respiratory system (R5 Hz), the central airways (R20 Hz), and peripheral airways (R5-20 Hz), which may trigger bronchoconstriction.

conclusionsHypertension is associated with impaired lung function and mechanics in older adults, and a physically active lifestyle attenuates these dysfunctions.

Indexed as

ExerciseHypertensionAgedCross-Sectional StudiesFemaleHumansLungMaleMiddle AgedQuality of LifeRespiratory Function TestsRespiratory Mechanicshealthy lungshypertensionphysical exerciserespiratory system

Identifiers

PMID39051189
PMCPMC11270291

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.