Evidence map›Paper›PMID 39051165›Full record

ArticleJournal of the American Chemical Society2024

Valence-Change MnO

Jingguo Wang, Siping Liang, Dongdong Zhu, Xiaocao Ma, Qin Peng, Guanzhao Wang, Yuting Wang, Tiantian Chen, Minhao Wu, Tony Y Hu and 1 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingguo WangZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Siping LiangZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Dongdong ZhuZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Xiaocao MaZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Qin PengZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Guanzhao WangSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangdong 510006, China.
Yuting WangZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Tiantian ChenZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Minhao WuZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.
Tony Y HuCenter of Cellular and Molecular Diagnosis, Tulane University School of Medicine, New Orleans, Louisiana 70112, United States.ORCID 0000-0002-5166-4937
Yuanqing ZhangZhongshan School of Medicine, Sun Yat-Sen University, Guangdong 510080, China.ORCID 0000-0002-8761-5328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heterogeneity of hepatocellular carcinoma (HCC) can prevent effective treatment, emphasizing the need for more effective therapies. Herein, we employed arsenene nanosheets coated with manganese dioxide and polyethylene glycol (AMPNs) for the degradation of Pin1, which is universally overexpressed in HCC. By employing an "AND gate", AMPNs exhibited responsiveness toward excessive glutathione and hydrogen peroxide within the tumor microenvironment, thereby selectively releasing As

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsManganese CompoundsNIMA-Interacting Peptidylprolyl IsomeraseOxidesAnimalsAntineoplastic AgentsArsenicalsCell Line, TumorEnzyme InhibitorsHumansMiceNanostructuresPolyethylene GlycolsAntineoplastic AgentsArsenicalsEnzyme InhibitorsManganese Compoundsmanganese dioxideNIMA-Interacting Peptidylprolyl IsomeraseOxidesPIN1 protein, humanPolyethylene Glycols

Identifiers

PMID39051165
PMCPMC11311233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.