Evidence map›Paper›PMID 39051076›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Compound

W Zhang, H Gu, P Chen, S Wu, H Ma, L Yao

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

W ZhangCollege of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830057, China.
H GuCollege of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830057, China.
P ChenCollege of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830057, China.
S WuCollege of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830057, China.
H MaCollege of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830057, China.
L YaoCollege of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830057, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the therapeutic mechanism of compound

methodsDrugbank, Gene Cards, OMIM and PharmGKb databases were used to obtain DCM-related targets, and the core targets were identified and functionally annotated by protein-protein interaction network analysis followed by GO and KEGG enrichment analysis. The "Traditional Chinese Medicine-Key Component-Key Target-Key Pathway" network was constructed using Cytoscape 3.9.1, and molecular docking was carried out for the key components and the core targets. In the animal experiment, Wistar rat models of DCM were treated with normal saline or

resultsWe identified 61 active compounds in

conclusionThe therapeutic effect of compound

Indexed as

ApoptosisDiabetes Mellitus, ExperimentalDiabetic CardiomyopathiesDrugs, Chinese HerbalInflammationMolecular Docking SimulationPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRats, WistarSignal TransductionAnimalsInterleukin-6MaleMyocardiumRatsDrugs, Chinese HerbalInterleukin-6Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktcompound Yuye Decoctiondiabetic cardiomyopathynetwork pharmacology

Identifiers

PMID39051076
PMCPMC11270665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.