Evidence map›Paper›PMID 39051068›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

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Z Ke, Z Huang, R He, Q Zhang, S Chen, Z K Cui, J Ding

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Z KeDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515 China.
Z HuangDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515 China.
R HeDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515 China.
Q ZhangDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515 China.
S ChenDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515 China.
Z K CuiDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515 China.
J DingDepartment of Pediatric Orthopedics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of high-mobility group AT-hook 2 (HMGA2) in osteogenic differentiation of adipose-derived mesenchymal stem cells (ADSCs) and the effect of

methodsBioinformatics studies using the GEO database and Rstudio software identified HMGA2 as a key factor in adipogenic-osteogenic differentiation balance of ADSCs. The protein-protein interaction network of HMGA2 in osteogenic differentiation was mapped using String and visualized with Cytoscape to predict the downstream targets of HMGA2. Primary mouse ADSCs (mADSCs) were transfected with

resultsGEO database analysis showed that

conclusionHMGA2 is a crucial regulator of osteogenic differentiation in ADSCs, and

Indexed as

Cell DifferentiationHMGA2 ProteinMesenchymal Stem CellsOsteogenesisAdipogenesisAdipose TissueAnimalsCore Binding Factor Alpha 1 SubunitGene Knockdown TechniquesMiceRNA, Small InterferingCore Binding Factor Alpha 1 SubunitHMGA2 ProteinRNA, Small Interferingadipose-derived mesenchymal stem cellsbone defect healinghigh-mobility group AT-hook 2osteogenic differentiation

Identifiers

PMID39051068
PMCPMC11270651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.