Evidence map›Paper›PMID 39051030›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2022

Explainable Contrastive Multiview Graph Representation of Brain, Mind, and Behavior.

Chongyue Zhao, Liang Zhan, Paul M Thompson, Heng Huang

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chongyue ZhaoDepartment of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Liang ZhanDepartment of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Paul M ThompsonImaging Genetics Center, University of Southern California, Los Angeles, CA, USA.
Heng HuangDepartment of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
Imaging Genomics Based Brain Disease PredictionR01AG049371 · NIA · UNIVERSITY OF TEXAS ARLINGTON · PI HUANG, HENG · 2015 to 2019
$2.0M
Connecting late-life depression and cognition with statistical physics based connectomics and sparse Frechet regressionRF1MH125928 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LEOW, ALEX, WU, YICHAO · 2021 to 2021
$1.3M
CRCNS: Investigating Brain Dynamics through the Lens of Statistical MechanicsR01AG071243 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEOW, ALEX, ZHAN, LIANG · 2020 to 2022
$882k
NIA NIH HHS R01 AG049371NIA NIH HHS R01 AG071243NIA NIH HHS U01 AG068057NIMH NIH HHS RF1 MH125928
6 · The paper itself

Abstract

Understanding the intrinsic patterns of human brain is important to make inferences about the mind and brain-behavior association. Electrophysiological methods (i.e. MEG/EEG) provide direct measures of neural activity without the effect of vascular confounds. The blood oxygenated level-dependent (BOLD) signal of functional MRI (fMRI) reveals the spatial and temporal brain activity across different brain regions. However, it is unclear how to associate the high temporal resolution Electrophysiological measures with high spatial resolution fMRI signals. Here, we present a novel interpretable model for coupling the structure and function activity of brain based on heterogeneous contrastive graph representation. The proposed method is able to link manifest variables of the brain (i.e. MEG, MRI, fMRI and behavior performance) and quantify the intrinsic coupling strength of different modal signals. The proposed method learns the heterogeneous node and graph representations by contrasting the structural and temporal views through the mind to multimodal brain data. The first experiment with 1200 subjects from Human connectome Project (HCP) shows that the proposed method outperforms the existing approaches in predicting individual gender and enabling the location of the importance of brain regions with sex difference. The second experiment associates the structure and temporal views between the low-level sensory regions and high-level cognitive ones. The experimental results demonstrate that the dependence of structural and temporal views varied spatially through different modal variants. The proposed method enables the heterogeneous biomarkers explanation for different brain measurements.

Indexed as

Brain dynamicsExplanations on graphsSpatio-temporal graphs

Identifiers

PMID39051030
PMCPMC11267032

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.