Evidence map›Paper›PMID 39050955›Full record

ArticleNanoscale advances2024

Exploiting residual cocoa biomass to extract advanced materials as building blocks for manufacturing nanoparticles aimed at alleviating formation-induced oxidative stress on human dermal fibroblasts.

Joel Girón-Hernández, Yeison Barrios Rodríguez, Noemi Corbezzolo, Dayana Orozco Blanco, Carlos Carranza Gutiérrez, William Cheung, Piergiorgio Gentile

Abstract read
In one paragraph

Article in Nanoscale advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joel Girón-HernándezDepartment of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University NE1 8ST Newcastle Upon Tyne UK joel.l.g.hernandez@northumbria.ac.uk.
Yeison Barrios Rodríguezi-Food, Instituto Universitario de Ingeniería de Alimentos-FoodUPV, Universitat Politècnica de València 46021 Valencia Spain.
Noemi CorbezzoloSchool of Engineering, Newcastle University NE1 7RU Newcastle Upon Tyne UK Piergiorgio.gentile@ncl.ac.uk.
Dayana Orozco BlancoCentro Surcolombiano de Investigación en Café (CESURCAFÉ), Universidad Surcolombiana 410010 Neiva Colombia.
Carlos Carranza GutiérrezEscuela de Ciencias Agrícolas, Pecuarias y del Medio Ambiente, Universidad Nacional Abierta a Distancia 111511 Bogotá Colombia.
William CheungDepartment of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University NE1 8ST Newcastle Upon Tyne UK joel.l.g.hernandez@northumbria.ac.uk.
Piergiorgio GentileSchool of Engineering, Newcastle University NE1 7RU Newcastle Upon Tyne UK Piergiorgio.gentile@ncl.ac.uk.ORCID https://orcid.org/0000-0002-3036-6594

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global adoption of by-product valorisation processes aligns with the circular economy framework, ensuring sustainability in the agricultural sector. In cocoa production, residual biomass can offer the opportunity to extract advanced materials, contributing to nanotherapeutic solutions for biomedical applications. This study explores extraction processes for valorising cocoa pod husks (CPHs) and optimising valuable cocoa-derived biocompounds for enhanced health benefits. Various extraction processes are compared, revealing the significant influence of CPH powder amount and extraction time. Furthermore, metabolic analysis identifies 124 compounds in the metabolite mix, including tartaric acid, gluconic acid and bioactive agents with antioxidant properties, resulting in a high total phenolic content of 3.88 ± 0.06 mg g

Identifiers

PMID39050955
PMCPMC11265571

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.