Evidence map›Paper›PMID 39050939›Full record

ArticleClinical hematology international2024

The EMMY longitudinal, cohort study: real-world data to describe multiple myeloma management and outcomes as more therapeutic options emerge.

Olivier Decaux, Ronan Garlantézec, Karim Belhadj-Merzoug, Margaret Macro, Laurent Frenzel, Aurore Perrot, Philippe Moreau, Bruno Royer, Denis Caillot, Xavier Leleu and 13 more

Abstract read
In one paragraph

Article in Clinical hematology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Olivier DecauxService d'hématologie clinique Centre Hospitalier Universitaire de Rennes.
Ronan GarlantézecSanté publique et épidémiologie Centre Hospitalier Universitaire de Rennes.
Karim Belhadj-MerzougUnité Fonctionnelle Hémopathies Lymphoïdes Centre Hospitalier Universitaire Henri-Mondor.
Margaret MacroService d'hématologie clinique Centre Hospitalier Universitaire de Caen.
Laurent FrenzelService d'hématologie adulte Hôpital Necker-Enfants Malades.
Aurore PerrotHématologie Centre Hospitalier Universitaire de Toulouse.
Philippe MoreauHématologie clinique CHRU - Hôtel Dieu (Nantes).
Bruno RoyerImmuno-Hématologie Hôpital Saint-Louis (Paris).
Denis CaillotHématologie Clinique Centre Hospitalier Universitaire Dijon Bourgogne.
Xavier LeleuHématologie Centre Hospitalier Universitaire de Poitiers.
Mohamad MohtyService d'Hématologie et Thérapie cellulaire Hôpital Saint-Antoine.
Lionel KarlinHématologie clinique Hospices Civils de Lyon.
Pierre FeugierService d'hématologie CHU de Nancy - Hôpitaux de Brabois.
Sophie RigaudeauService d'Hématologie CHV André Mignot.
Jean FontanService Hématologie CHRU Jean Minjoz (Besançon).
Cécile SonntagDépartement d'Hématologie et Oncologie Hôpitaux Universitaires de Strasbourg.
Laure VincentDépartement d'hématologie clinique CHU Montpellier.
Thomas ChalopinHématologie thérapie cellulaire CHRU de Tours.
Herve Avet LoiseauIUCT Oncopole Toulouse.
Zakaria MaaroufIntergroupe Francophone du Myélome.
Louni ChanazIntergroupe Francophone du Myélome.
Nathalie TexierEpidémiologie Kappa Santé.
Cyrille HulinHématologie Hôpital Haut-Lévêque (Pessac).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic management of patients with multiple myeloma (MM) is complex. Despite substantial advances, MM remains incurable, and management involves cycles of treatment response, disease relapse, and further therapy. Currently, evidence to support the therapeutic decision is limited. Thus, the EMMY longitudinal, real-world study was designed to annually assess therapeutic management of MM in France to provide evidence to support physicians. During an annual prespecified 3-month recruitment period, eligible patients will be identified from their medical records. Adults aged ≥18 years diagnosed with symptomatic MM and requiring systemic treatment will be eligible. The primary objective, the evolution of MM therapeutic management, will be described, as well as the impact on the following outcomes: time-to-next treatment (TTNT), progression-free survival (PFS), and overall survival (OS). The study plans to recruit 5000 patients over 6 years: 700 to 900 patients annually. EMMY is a unique opportunity to collect real-world data to describe the evolving MM therapeutic landscape and record outcomes in France. These data will provide annual snapshots of various aspects of MM management. This knowledge will provide physicians with real-life, evidence-based data for therapeutic decision-making and ultimately improve treatment for MM patients.

Indexed as

Multiple myelomareal-world datatherapeutic management

Identifiers

PMID39050939
PMCPMC11268993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.