Evidence map›Paper›PMID 39050911›Full record

ArticleEuropean urology open science2024

Navigating the Aftermath: A Comprehensive Scoping Review on Follow-up Strategies After Kidney-sparing Surgery for Upper Tract Urothelial Carcinoma.

Hugo W Schuil, Orlane J A Figaroa, Nora Hendriks, Barbara M A Schout, Harrie P Beerlage, Faridi S van Jamaludin, Michaël M E L Henderickx, R Jeroen A van Moorselaar, Guido M Kamphuis, Joyce Baard

Abstract readScoping Review
In one paragraph

Article in European urology open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hugo W SchuilDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Orlane J A FigaroaDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Nora HendriksDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Barbara M A SchoutDepartment of Urology, Alrijne Hospital, Leiderdorp, The Netherlands.
Harrie P BeerlageDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Faridi S van JamaludinMedical Library AMC, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Michaël M E L HenderickxDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
R Jeroen A van MoorselaarCancer Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Guido M KamphuisDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Joyce BaardDepartment of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Upper tract urothelial carcinoma (UTUC) can be managed efficiently and safely through kidney-sparing surgery (KSS) in selected patient groups. However, the most effective and efficient postoperative surveillance strategy remains undetermined. We aimed to provide a comprehensive synopsis of the follow-up strategies and survival outcomes in patients diagnosed with UTUC treated by KSS. Methods: Following the systematic methodology outlined in the Preferred Reporting Items for Systematic Reviews and Meta-analyses Extension for Scoping Reviews, we conducted searches in four databases (MEDLINE [Ovid], Embase [Ovid], Cochrane Library, and Web of Science) up until December 11, 2023. Key findings and limitations: A total of 3121 articles underwent screening, of which 19 were selected for inclusion in this review. The follow-up schedules after KSS exhibited considerable variability among the included studies. Diagnostic modalities employed consisted of computed tomography urography (present in 84% of protocols), X urography (21%), ultrasound (21%), thoracic imaging (26%), voided urine cytology (89%), selective upper tract cytology (5.3%), cystoscopy (84%), and ureterorenoscopy (53%) at varying frequencies. At 5 yr of follow-up, the reported recurrence-free survival rate ranged from 30% to 86%, overall survival was 50-92%, and metastasis-free survival was 77-90%. Conclusions and clinical implications: This review unveils significant heterogeneity in clinical practices and survival outcomes, indicating disparities between real-world approaches and guideline recommendations. The lack of consensus on follow-up schemes is evident, emphasising the necessity for future initiatives aimed at developing a comprehensive protocol. Patient summary: This review shows significant heterogeneity in follow-up strategies after kidney-sparing surgery for upper tract urothelial carcinoma. A lack of evidence contributes to discrepancies between guidelines and real-world approaches. Thus, future endeavours should aim at establishing a comprehensive protocol.

Indexed as

Follow-upKidney-sparing surgeryReviewSurvivalUpper tract urothelial carcinoma

Identifiers

PMID39050911
PMCPMC11268123

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.