Evidence map›Paper›PMID 39050733›Full record

ReviewFrontiers in molecular biosciences2024

Understanding the impact of

Robin Lenk, Werner Kleindienst, Gábor Tamás Szabó, Markus Baiersdörfer, Gábor Boros, Jason M Keller, Azita J Mahiny, Irena Vlatkovic

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. IntegratedMolecular therapy. Nucleic acids · 2026
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  15. Immunology of RNA-based vaccines: The critical interplay between inflammation and expression.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robin Lenk *BioNTech SE, Mainz, Germany.
Werner Kleindienst *BioNTech SE, Mainz, Germany.
Gábor Tamás SzabóBioNTech SE, Mainz, Germany.
Markus BaiersdörferBioNTech SE, Mainz, Germany.
Gábor BorosBioNTech SE, Mainz, Germany.
Jason M KellerBioNTech SE, Mainz, Germany.
Azita J MahinyBioNTech SE, Mainz, Germany.
Irena VlatkovicBioNTech SE, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The success of messenger (m)RNA-based vaccines against SARS-CoV-2 during the COVID-19 pandemic has led to rapid growth and innovation in the field of mRNA-based therapeutics. However, mRNA production, whether in small amounts for research or large-scale GMP-grade for biopharmaceutics, is still based on the

Indexed as

abortive transcriptsdouble-stranded RNA (dsRNA)in vitro transcription reaction (IVT)IVT byproductsIVT contaminantsmRNA purification

Identifiers

PMID39050733
PMCPMC11266732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.