Evidence map›Paper›PMID 39050615›Full record

ArticleJournal of biomedical optics2024

Detection and margin assessment of thyroid carcinoma with microscopic hyperspectral imaging using transformer networks.

Minh Ha Tran, Ling Ma, Hasan Mubarak, Ofelia Gomez, James Yu, Michelle Bryarly, Baowei Fei

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minh Ha TranUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.ORCID 0000-0002-9936-9654
Ling MaUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.ORCID 0000-0002-4352-5697
Hasan MubarakUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.ORCID 0000-0002-1141-3471
Ofelia GomezUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.
James YuUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.ORCID 0009-0009-8398-1919
Michelle BryarlyUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.ORCID 0009-0000-3739-1314
Baowei FeiUniversity of Texas at Dallas, Department of Bioengineering, Richardson, Texas, United States.ORCID 0000-0002-9123-9484

Funding

ACADEMIC-INDUSTRIAL PARTNERSHIP FOR TRANSLATION OF PET/TRUS GUIDED INTERVENTIONR01CA204254 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2017 to 2021
$2.0M
A Real-Time Hyperspectral Laparoscopic Stereo Imaging System for Robot-Assisted SurgeryR01CA288379 · NCI · UNIVERSITY OF TEXAS DALLAS · PI BAOWEI FEI · 2024 to 2026
$1.6M
Training Clinician Scientists as Outstanding Clinicians and Imaging ScientistsT32EB028093 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI ROBERT F MATTREY, Takeshi Yokoo · 2019 to 2026
$1.5M
NCI NIH HHS R01 CA204254NCI NIH HHS R01 CA288379NIBIB NIH HHS T32 EB028093
6 · The paper itself

Abstract

Significance: Hyperspectral imaging (HSI) is an emerging imaging modality for oncological applications and can improve cancer detection with digital pathology. Aim: The study aims to highlight the increased accuracy and sensitivity of detecting the margin of thyroid carcinoma in hematoxylin and eosin (H&E)-stained histological slides using HSI and data augmentation methods. Approach: Using an automated microscopic imaging system, we captured 2599 hyperspectral images from 65 H&E-stained human thyroid slides. Images were then preprocessed into 153,906 image patches of dimension Results: In the testing dataset, TimeSformer achieved an accuracy of 90.87%, a weighted Conclusions: The TimeSformer model trained with hyperspectral histological data consistently outperformed conventional RGB-based models, highlighting the superiority of HSI in this context. Our proposed augmentation methods improved the accuracy, the

Indexed as

Hyperspectral ImagingThyroid NeoplasmsAlgorithmsHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMicroscopyNeural Networks, ComputerThyroid Glandhyperspectral imagingmargin detectionmicroscopethyroid carcinomatransformer

Identifiers

PMID39050615
PMCPMC11268383

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.