Evidence map›Paper›PMID 39050552›Full record

ArticleRegenerative therapy2024

Sustainably cultured coral scaffold supports human bone marrow mesenchymal stromal cell osteogenesis.

Chiara Gentili, Maria Elisabetta Federica Palamà, Gillian Sexton, Sophie Maybury, Megan Shanahan, Yeyetunde Yvonne Omowunmi-Kayode, James Martin, Martin Johnson, Kerry Thompson, Owen Clarkin and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chiara GentiliDepartment of Experimental Medicine (DIMES), University of Genova, Genova, Italy.
Maria Elisabetta Federica PalamàDepartment of Experimental Medicine (DIMES), University of Genova, Genova, Italy.
Gillian SextonCollege of Medicine, Nursing and Health Science, School of Medicine, Regenerative Medicine Institute (REMEDI), University of Galway, Galway, Ireland.
Sophie MayburyCollege of Medicine, Nursing and Health Science, School of Medicine, Regenerative Medicine Institute (REMEDI), University of Galway, Galway, Ireland.
Megan ShanahanCollege of Medicine, Nursing and Health Science, School of Medicine, Regenerative Medicine Institute (REMEDI), University of Galway, Galway, Ireland.
Yeyetunde Yvonne Omowunmi-KayodeDCU Biomaterials Research Group, Centre for Medical Engineering Research, School of Mechanical and Manufacturing Engineering, Dublin City University, Dublin 9, Ireland.
James MartinZoan Nuáil Teoranta T/A Zoan BioMed, The Hatchery Building, Cloonacarton, Recess, Galway, Ireland.
Martin JohnsonZoan Nuáil Teoranta T/A Zoan BioMed, The Hatchery Building, Cloonacarton, Recess, Galway, Ireland.
Kerry ThompsonCollege of Medicine, Nursing and Health Science, School of Medicine, Anatomy Imaging and Microscopy Facility, University of Galway, Galway, Ireland.
Owen ClarkinDCU Biomaterials Research Group, Centre for Medical Engineering Research, School of Mechanical and Manufacturing Engineering, Dublin City University, Dublin 9, Ireland.
Cynthia M ColemanCollege of Medicine, Nursing and Health Science, School of Medicine, Regenerative Medicine Institute (REMEDI), University of Galway, Galway, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current gold standard grafting material is autologous bone due to its osteoinductive and osteoconductive properties. Autograft harvesting results in donors site morbidity. Coral scaffolds offer a natural autograft alternative, sharing the density and porosity of human bone. This study investigated the biocompatibility and osteogenic potential of a novel, sustainably grown

Indexed as

BoneBone grafting substituteCoral scaffoldMesenchymal stem cellMesenchymal stromal cellOsteogenesis

Identifiers

PMID39050552
PMCPMC11267040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.