ArticleFrontiers in chemistry2024
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates.
Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- 1,4-Pentanediol as an Alternative Biomass-Derived Medium for the Phosphine-Free Heck Coupling Reactions.ChemSusChem · 2026Article
- Ruthenium(II)-Catalyzed Alkenylation of Primary Arylacetamides: En Route Synthesis of Trisubstituted Alkenes.Chemistry, an Asian journal · 2026Article
- Recyclable Palladium-Polysiloxane Catalyst with Ultra-Low Metal Leaching for Drug Synthesis.Polymers · 2025Article
- The stereo-divergent functionalization of alkynes: a comprehensive review.RSC advances · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Heck reaction is widely employed to build a variety of biologically relevant scaffolds and has been successfully implemented in the production of active pharmaceutical ingredients (APIs). Typically, the reaction with terminal alkenes gives high yields and stereoselectivity toward the
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Registered trials
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