Evidence map›Paper›PMID 39049965›Full record

ArticleMedComm2024

Gallium complex K6 inhibits colorectal cancer by increasing ROS levels to induce DNA damage and enhance phosphatase and tensin homolog activity.

Wei Li, Chuanyu Yang, Zhuo Cheng, Yuanyuan Wu, Sihan Zhou, Xiaowei Qi, Yi Zhang, Jinhui Hu, Mingjin Xie, Ceshi Chen

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Wei LiYunnan Key Laboratory of Animal Models and Human Disease Mechanisms Kunming Institute of Zoology Chinese Academy of Sciences Kunming China.
Chuanyu YangYunnan Key Laboratory of Animal Models and Human Disease Mechanisms Kunming Institute of Zoology Chinese Academy of Sciences Kunming China.
Zhuo ChengYunnan Key Laboratory of Animal Models and Human Disease Mechanisms Kunming Institute of Zoology Chinese Academy of Sciences Kunming China.
Yuanyuan WuSchool of Chemical Science and Technology Yunnan University Kunming China.
Sihan ZhouSchool of Chemical Science and Technology Yunnan University Kunming China.
Xiaowei QiDepartment of Breast and Thyroid Surgery Southwest Hospital The First Affiliated Hospital of the Army Military Medical University Chongqing China.
Yi ZhangDepartment of Breast and Thyroid Surgery Southwest Hospital The First Affiliated Hospital of the Army Military Medical University Chongqing China.
Jinhui HuThe First Hospital of Hunan University of Chinese Medicine Changsha China.
Mingjin XieSchool of Chemical Science and Technology Yunnan University Kunming China.
Ceshi ChenAcademy of Biomedical Engineering Kunming Medical University Kunming China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common malignancies worldwide. In the clinical realm, platinum-based drugs hold an important role in the chemotherapy of CRC. Nonetheless, a multitude of patients, due to tumor protein 53 (

Indexed as

colorectal cancerdeoxyribonucleic acid (DNA) damagegallium complex k6phosphatase and tensin homolog (PTEN)reactive oxygen species (ROS)

Identifiers

PMID39049965
PMCPMC11266899

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.