Evidence map›Paper›PMID 39049899›Full record

ArticleActa biochimica Polonica2024

Application of the FISH method and high-density SNP arrays to assess genetic changes in neuroblastoma-research by one institute.

Dorota Winnicka, Paulina Skowera, Magdalena Stelmach, Borys Styka, Monika Lejman

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In one paragraph

Article in Acta biochimica Polonica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dorota Winnicka *Independent Laboratory of Genetic Diagnostics, Medical University of Lublin, Lublin, Poland.
Paulina Skowera *Independent Laboratory of Genetic Diagnostics, Medical University of Lublin, Lublin, Poland.
Magdalena StelmachIndependent Laboratory of Genetic Diagnostics, Medical University of Lublin, Lublin, Poland.
Borys StykaIndependent Laboratory of Genetic Diagnostics, Medical University of Lublin, Lublin, Poland.
Monika LejmanIndependent Laboratory of Genetic Diagnostics, Medical University of Lublin, Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is the most common extracranial solid tumor in children. Amplification of the MYCN gene has been observed in approximately 20%-30% of tumors. It is strongly correlated with advanced-stage disease, rapid tumor progression, resistance to chemotherapy and poor outcomes independent of patient age and stage of advanced disease. MYCN amplification identifies high-risk patients. To assess neuroblastoma tumors with MYCN amplification we used paraffin-embedded tissue sections in 57 patients and intraoperative tumor imprints in 10 patients by fluorescence

Indexed as

Gene AmplificationIn Situ Hybridization, FluorescenceNeuroblastomaN-Myc Proto-Oncogene ProteinPolymorphism, Single NucleotideChildChild, PreschoolFemaleHumansInfantMaleMYCN protein, humanN-Myc Proto-Oncogene Proteinchildhood tumoursFISHhigh-density SNP arraysMYCN amplificationneuroblastoma

Identifiers

PMID39049899
PMCPMC11267511

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.