Evidence map›Paper›PMID 39049729›Full record

ArticleRenal failure2024

Bone marrow-derived mesenchymal stem cells reduce CCl

Asmaa Adel, Manal Abdul-Hamid, Samraa H Abdel-Kawi, Mohamed A Abdelaziz, Hader I Sakr, Osama M Ahmed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asmaa AdelHistology, Cell Biology and Genetic Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.
Manal Abdul-HamidHistology, Cell Biology and Genetic Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.ORCID 0000-0002-0877-3097
Samraa H Abdel-KawiMedical Histology and Cell Biology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Mohamed A AbdelazizBasic Medical Sciences Department, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.
Hader I SakrDepartment of Medical Physiology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Osama M AhmedMolecular Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study explores the possible therapeutic role of rats and mice bone marrow-derived mesenchymal stem cells (BM-MSCs) on renal damage and toxicity brought on by carbon tetrachloride (CCl

methodsFollowing an intraperitoneal injection of CCl

resultsIn CCl

conclusionsBy boosting antioxidant defense and reducing apoptosis and inflammation, BM-MSCs from mice and rats were able to enhance kidney function and histological integrity in rats that had received CCl

Indexed as

Carbon TetrachlorideFibrosisKidneyMesenchymal Stem CellsAcute Kidney InjuryAnimalsCyclooxygenase 2Disease Models, AnimalLipid PeroxidationMaleMesenchymal Stem Cell TransplantationMiceOxidative StressRatsRats, WistarTumor Necrosis Factor-alphaCarbon TetrachlorideCyclooxygenase 2Tumor Necrosis Factor-alphaBM-MSCsCCl4inflammatory and apoptotic markersKidney toxicityoxidative stressrats

Identifiers

PMID39049729
PMCPMC11275530

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.