Evidence map›Paper›PMID 39049441›Full record

ArticleAmerican journal of epidemiology2024

Participation in Physical, Cognitive, and Social Activities and the Association with Mobility Disability Transitions in Older Adults.

Brittney S Lange-Maia, Tianhao Wang, Victoria N Poole, Melissa Lamar, Raj C Shah, Lisa L Barnes, Bryan D James

Abstract read
In one paragraph

Article in American journal of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brittney S Lange-MaiaRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0001-6642-7558
Tianhao WangRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0002-1831-8266
Victoria N PooleRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0003-0974-2564
Melissa LamarRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0001-6130-5543
Raj C ShahRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0001-9706-9730
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0002-0072-9817
Bryan D JamesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States.ORCID 0000-0003-1932-151X

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
A Multi-modal Imaging Model to Predict Mobility in Older AdultsK01AG064044 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI POOLE, VICTORIA N · 2019 to 2021
$377k
Multilevel Contributors to Cognitive and Physical Function Decline in Older African AmericansR03AG071943 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LANGE MAIA, BRITTNEY SUSANNE · 2021 to 2021
$308k
NIA NIH HHS K01 AG064044NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R03 AG071943
6 · The paper itself

Abstract

Development of late-life mobility disability is a dynamic process of transitions between worsening and improving. We tested associations between participation in physical, social, and cognitive activity with mobility disability transitions. Participants (N=2,758, age 78.1 years [SD: 7.7]) from two Rush Alzheimer's Disease Center cohorts completed annual mobility disability questionnaires for 7.6 (SD: 4.4) years. First-order Markov transition models tested associations between baseline self-reported physical, social, and cognitive activity with bidirectional transitions in mobility disability score increases (worsening) and decreases (improving) between consecutive visits. Overall, 75.5% of participants experienced ≥1 transition among 18,318 pairs of consecutive visits-4,174 of which were worsening and 2,606 were improving transitions. Adjusting for covariates, higher participation in each activity type was associated with lower odds of worsening (physical OR=0.71, 95% CI: 0.67-0.75; social OR=0.64, 95% CI: 0.58-0.70; and cognitive OR=0.79, 95% CI: 0.74-0.85), and higher odds of improving (physical OR=1.20, 95% CI: 1.11-1.28; social OR=1.45, 95% CI: 1.30-1.61; and cognitive OR=1.12, 95% CI: 1.03-1.22) in separate models. In combined models, physical and social activity remained associated with worsening and improving; cognitive activity was only associated with worsening. Physical, social, and cognitive activity engagement contributes to lower odds of worsening mobility disability and may promote recovery.

Indexed as

Aginglate lifelifestyle behaviorsMarkov transition modelingmobility disability

Identifiers

PMID39049441
PMCPMC12234217

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.