Evidence map›Paper›PMID 39049190›Full record

ArticleActa obstetricia et gynecologica Scandinavica2024

Maternal hemoglobin drop in multiple pregnancy is associated with higher gestational age at birth and birthweight.

Kristin Townsend, Tanya Maric, Philip J Steer, Makrina D Savvidou

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristin TownsendFaculty of Medicine, Imperial College London, London, UK.ORCID 0009-0002-9217-6427
Tanya MaricFetal Medicine Unit, Chelsea & Westminster Hospital, London, UK.
Philip J SteerAcademic Department of Obstetrics and Gynaecology, Chelsea & Westminster Hospital, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Makrina D SavvidouFetal Medicine Unit, Chelsea & Westminster Hospital, London, UK.ORCID 0000-0002-0125-2299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis retrospective study investigated the hypothesis that maternal hemoglobin (Hb) levels in twin pregnancy fall between the first and second trimesters and that higher falls are associated with higher gestational age at birth and higher birthweight (BW). MATERIAL AND

methodsThe study population was defined as pregnant women with twin pregnancies delivering two live, phenotypically normal neonates, after 24

results923 pregnant women with twin pregnancies were included. Maternal Hb1 did not correlate with any outcomes measured. However, a lower Hb2 and a larger Hb drop was associated with a higher gestational age at birth (p < 0.001), a larger BW of twin 1 and 2 (p < 0.001 for both) and a reduction in the incidence of delivering one or two SGA neonates (p < 0.001 for both). MCV values did not correlate significantly with these outcomes.

conclusionsThis study showed that in twin pregnancy, a larger maternal Hb drop from the first to the second trimester is associated with a higher gestational age at birth and a larger BW. This change may represent a larger plasma volume expansion.

Indexed as

Birth WeightGestational AgeHemoglobinsAdultFemaleHumansInfant, NewbornInfant, Small for Gestational AgeLondonPregnancyPregnancy, MultiplePregnancy, TwinRetrospective StudiesHemoglobinsbirthweightmaternal hemoglobinpregnancytwin

Identifiers

PMID39049190
PMCPMC11426208

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.