Evidence map›Paper›PMID 39049014›Full record

ReviewChinese medicine2024

Biosynthesis and signal transduction of plant growth regulators and their effects on bioactive compound production in Salvia miltiorrhiza (Danshen).

Heqin Li, Xuwen Jiang, Kiyoshi Mashiguchi, Shinjiro Yamaguchi, Shanfa Lu

Abstract readReview
In one paragraph

Review in Chinese medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Adventitious and Hairy Root Cultures ofInternational journal of molecular sciences · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heqin LiCollege of Agronomy, Qingdao Agricultural University, No. 700 Changcheng Road, Chengyang District, Qingdao, 266109, Shandong, People's Republic of China.ORCID http://orcid.org/0000-0002-6859-2343
Xuwen JiangCollege of Agronomy, Qingdao Agricultural University, No. 700 Changcheng Road, Chengyang District, Qingdao, 266109, Shandong, People's Republic of China.ORCID http://orcid.org/0000-0003-3537-9631
Kiyoshi MashiguchiInstitute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan.ORCID http://orcid.org/0000-0002-7234-887X
Shinjiro YamaguchiInstitute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan. shinjiro@scl.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0002-0786-1757
Shanfa LuInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 151 Malianwa North Road, Haidian District, Beijing, 100193, People's Republic of China. sflu@implad.ac.cn.ORCID http://orcid.org/0000-0001-6284-4389

Funding

National Natural Science Foundation of China 31801906Qingdao Applied Basic Research Program for Young Talents 19-6-2-36-cgShandong Provincial Government joins with Qingdao Agricultural University's Overseas Study Program 2020079
6 · The paper itself

Abstract

Plant growth regulators (PGRs) are involved in multiple aspects of plant life, including plant growth, development, and response to environmental stimuli. They are also vital for the formation of secondary metabolites in various plants. Salvia miltiorrhiza is a famous herbal medicine and has been used commonly for > 2000 years in China, as well as widely used in many other countries. S. miltiorrhiza is extensively used to treat cardiovascular and cerebrovascular diseases in clinical practices and has specific merit against various diseases. Owing to its outstanding medicinal and commercial potential, S. miltiorrhiza has been extensively investigated as an ideal model system for medicinal plant biology. Tanshinones and phenolic acids are primary pharmacological constituents of S. miltiorrhiza. As the growing market for S. miltiorrhiza, the enhancement of its bioactive compounds has become a research hotspot. S. miltiorrhiza exhibits a significant response to various PGRs in the production of phenolic acids and tanshinones. Here, we briefly review the biosynthesis and signal transduction of PGRs in plants. The effects and mechanisms of PGRs on bioactive compound production in S. miltiorrhiza are systematically summarized and future research is discussed. This article provides a scientific basis for further research, cultivation, and metabolic engineering in S. miltiorrhiza.

Indexed as

DanshenPhenolic acidsPlant growth regulatorsSalvia miltiorrhizaTanshinones

Identifiers

PMID39049014
PMCPMC11267865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.