Evidence map›Paper›PMID 39048969›Full record

ArticleBMC infectious diseases2024

Time-dependent analysis of erectile dysfunction in kidney transplant recipients: insights from four distinct time periods.

Jiashan Pan, Zhenming Zheng, Wenbo Wang, Dekai Hu, Rui Yao, Yiding Chen, Handong Ding, Jinbiao Zhong, Zongyao Hao, Guiyi Liao

Abstract read
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiashan Pan *Department of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Zhenming Zheng *Department of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Wenbo Wang *Department of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Dekai HuDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Rui YaoDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Yiding ChenDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Handong DingDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Jinbiao ZhongDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
Zongyao HaoDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China. haozongyao@ahmu.edu.cn.
Guiyi LiaoDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China. liaoguiyi@ahmu.edu.cn.ORCID http://orcid.org/0000-0002-0415-5515

Funding

National Natural Science Foundation of China 82070724Natural Science Research Project of Anhui Educational Committee 2023AH040372
6 · The paper itself

Abstract

background and intentionErectile dysfunction (ED) is an underappreciated clinical condition in men. This study aims to compare the dynamic changes in the distribution of ED among male kidney transplant recipients (mKTRs) in four epochs: end-stage renal disease period (ESRDp), early post-transplant period (EPTP), pre-COVID-19, and post-COVID-19.

methodsGeneral information was gathered through interviews, follow-ups, and medical records. The International Index of Erectile Function Questionnaire-5 was used to assess erectile function. The Mann-Whitney U test and chi-square test were used to analyze differences in ED strength. Univariate and logistic regression analyses were conducted to identify risk factors for ED.

resultsThe database contains 230 mKTRs. In the ESRDp, 17.0% had normal erectile function, 53.5% had mild ED, 18.3% had moderate ED, and 11.3% had severe ED. In the EPTP, the distribution was 38.2% normal, 42.6% mild, 10.8% moderate, and 8.2% severe. In the pre-COVID-19 period, it was 34.3%, 47.3%, 10.4%, and 7.8%, and in the post-COVID-19 period, it was 23.0%, 45.6%, 21.3%, and 10.0%. Overall, erectile function improved after kidney transplant (KT). However, post-COVID-19, the proportion of erectile function significantly decreased compared to EPTP and pre-COVID-19 periods. Risk factors for post-pandemic ED included degree, Generalized Anxiexy Disorder-7, kidney donor type, postoperative time, hypertension and hemoglobin concentration.

conclusionKT improves erectile function in mKTRs within 5 years, but post-SARS-CoV-2 viral infection, ED worsens due to altered risk factors. These findings inform future research for comprehensive ED prevention and management strategies in this population.

Indexed as

COVID-19Erectile DysfunctionKidney TransplantationTransplant RecipientsAdultAgedHumansKidney Failure, ChronicMaleMiddle AgedRisk FactorsSARS-CoV-2Surveys and QuestionnairesTime FactorsErectile DysfunctionInternational Index of Erectile Function Questionnaire-5Kidney TransplantSARS-CoV-2

Identifiers

PMID39048969
PMCPMC11267971

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.