ArticleBMC neurology2024
Association between fibrinogen levels and stroke-associated pneumonia in acute ischemic stroke patients.
Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Advances in stroke-associated pneumonia in the era of revascularization therapy.Chinese medical journal · 2026Review
- Predicting stroke-associated pneumonia for acute ischemic stroke patients post intravenous thrombolysis: the post-IVT-SAP risk score.Frontiers in medicine · 2026Article
- Emerging Biosensor Technologies for Stroke Biomarker Detection: A Comprehensive Overview.Analytical science advances · 2025Review
- From Stroke to Infection: The Emerging Role of Fibrinogen-to-Albumin Ratio in Predicting Stroke-Associated Pneumonia.Cureus · 2025Article
- Association between fibrinogen-to-albumin ratio and all-cause mortality in critically ill patients with atrial fibrillation: a retrospective study using the MIMIC-IV database.European journal of medical research · 2025Article
- Risk factors of stroke-associated pneumonia in patients with acute ischemic stroke treated by endovascular thrombectomy.BMC neurology · 2025Article
- Associations between fibrinogen levels and the risk of all-cause mortality: a long-term cohort study.Journal of thrombosis and thrombolysis · 2025Article
- Threshold Effect of the Lymphocyte to HDL-C Ratio on the Risk of Stroke-Associated Pneumonia After Acute Ischemic Stroke: A Retrospective Cohort Study.Journal of inflammation research · 2025Article
- Emerging biomarkers in ischemic stroke.Vessel plus · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposePrior research had indicated a relationship between fibrinogen and stroke-associated pneumonia (SAP), yet the nature of this relationship had not been thoroughly investigated. Therefore, this study was designed to elucidate the prognostic value of fibrinogen levels in forecasting the occurrence of SAP among patients with acute ischemic stroke (AIS). PATIENTS AND
methodsIn this retrospective cross-sectional analysis, we included 1092 patients who had experienced AIS and were admitted to our facility within 72 h of the onset of their symptoms. Based on the SAP diagnostic criteria, patients were classified into two groups: SAP and non-SAP. The correlation between serum fibrinogen concentration and SAP was examined using univariate analysis. Curve fitting and multivariable logistic regression model were utilized for statistical evaluation.
resultsOut of the ischemic stroke patients included in the study, SAP was identified in 112 (10.26%) patients. A direct correlation was observed between fibrinogen levels and the incidence of SAP. An increase in fibrinogen levels corresponded with a heightened incidence of SAP. Multivariable logistic regression revealed a significant positive association between fibrinogen levels and SAP incidence (OR = 1.53, 95% confidence interval [CI]: 1.18, 1.99)).
conclusionA linear relationship between serum fibrinogen levels and the incidence of SAP in ischemic stroke patients was shown. The serum fibrinogen levels were positively and linearly correlated to SAP risk.
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