Evidence map›Paper›PMID 39048843›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Pre-operative spinal cord perfusion quantified by DSC MRI as a predictor of post-operative prognosis in patients with cervical spondylotic myelopathy.

Qingpeng Song, Chunyao Wang, Wen Jiang, Jinchao Wang, Jiuheng Li, Hua Guo, Huijun Chen, Xiao Han

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

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8 authors.

Qingpeng Song *Department of Spine Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Chunyao Wang *Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Wen JiangDepartment of Radiology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Jinchao WangDepartment of Spine Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Jiuheng LiBeijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Hua GuoCenter for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Huijun ChenCenter for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. chenhj_cbir@mail.tsinghua.edu.cn.
Xiao HanDepartment of Spine Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China. hanxiaomd@vip.163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to investigate the potential of preoperative blood supply condition measured by dynamic susceptibility contract (DSC) MRI in prediction of postoperative outcomes for patients with cervical spondylotic myelopathy (CSM). MATERIALS AND

methodThirty-nine patients (Age: 61 ± 7, male: 23, female: 16) with CSM who underwent laminoplasty were enrolled. All patients received DSC MRI before the operation. Five parameters include Enhance, rEnhance, full width at half maxima (FWHM), Slope1 and Slope2 in DSC MRI, were calculated at all the compressed spinal cord segments. Clinical outcomes were evaluated by modified Japanese Orthopaedic Association (mJOA) scores. Patients were divided into two groups based on mJOA recovery rate of 5 years: good recovery (> 50%) or poor recovery (≤ 50%). The difference between two groups were compared. The value of DSC MRI to CSM was evaluated by logistic and receiver operating characteristic (ROC) curve analysis.

resultsThere were 26 patients in good recovery group and 13 patients in poor recovery group. The baseline characteristics, including age, gender, preoperative mJOA score, and smoking status showed no significant difference between the two groups (all p > 0.05). The FWHM was significantly higher in the poor recovery group (9.77 ± 2.78) compared to the good recovery group (6.64 ± 1.65) (p = 0.002). Logistic regression analysis indicated that an increased FWHM was a significant risk factor for poor prognosis recovery (p = 0.013, OR = 0.392, 95%CI: 0.187-0.822). The AUC of FWHM for ROC was 0.843 (95% CI: 0.710-0.975) with a p value of 0.001. In addition, an FWHM greater than 5.87, with a sensitivity of 92.3% and specificity of 69.2%, was found to be an independent risk factor for poor postoperative recovery in patients with CSM.

conclusionIn this study, we successfully quantified the spinal cord blood supply condition by DSC MRI technique. We found that an increase in FWHM was an independent risk factor for poor postoperative recovery in CSM patients. Specifically, patients with FWHM > 5.87 have a poor postoperative recovery.

Indexed as

Cervical VertebraeMagnetic Resonance ImagingSpondylosisAgedFemaleHumansLaminoplastyMaleMiddle AgedPredictive Value of TestsPrognosisSpinal CordSpinal Cord DiseasesTreatment OutcomeCervical spondylotic myelopathyDynamic susceptibility contractLaminoplastyPerfusion-weighted magnetic resonance imagingPrognosis

Identifiers

PMID39048843

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