Evidence map›Paper›PMID 39048837›Full record

ReviewNature reviews. Microbiology2024

Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions.

Derek Cocker, Gabriel Birgand, Nina Zhu, Jesus Rodriguez-Manzano, Raheelah Ahmad, Kondwani Jambo, Anna S Levin, Alison Holmes

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  18. Persistent multispecies dissemination ofJournal of clinical microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Derek Cocker *David Price Evans Infectious Diseases & Global Health Group, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0002-6670-2713
Gabriel Birgand *Centre d'appui pour la Prévention des Infections Associées aux Soins, Nantes, France.
Nina ZhuNational Institute for Health and Care Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-6822-2708
Jesus Rodriguez-ManzanoNational Institute for Health and Care Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London, London, UK.
Raheelah AhmadNational Institute for Health and Care Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London, London, UK.
Kondwani JamboMalawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.
Anna S LevinDepartment of Infectious Disease, School of Medicine & Institute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
Alison HolmesDavid Price Evans Infectious Diseases & Global Health Group, University of Liverpool, Liverpool, UK. alison.holmes@liverpool.ac.uk.ORCID http://orcid.org/0000-0001-5554-5743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a global health challenge that threatens humans, animals and the environment. Evidence is emerging for a role of healthcare infrastructure, environments and patient pathways in promoting and maintaining AMR via direct and indirect mechanisms. Advances in vaccination and monoclonal antibody therapies together with integrated surveillance, rapid diagnostics, targeted antimicrobial therapy and infection control measures offer opportunities to address healthcare-associated AMR risks more effectively. Additionally, innovations in artificial intelligence, data linkage and intelligent systems can be used to better predict and reduce AMR and improve healthcare resilience. In this Review, we examine the mechanisms by which healthcare functions as a driver, reservoir and amplifier of AMR, contextualized within a One Health framework. We also explore the opportunities and innovative solutions that can be used to combat AMR throughout the patient journey. We provide a perspective on the current evidence for the effectiveness of interventions designed to mitigate healthcare-associated AMR and promote healthcare resilience within high-income and resource-limited settings, as well as the challenges associated with their implementation.

Indexed as

Delivery of Health CareAnimalsAnti-Bacterial AgentsDrug Resistance, BacterialHumansAnti-Bacterial Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.