Evidence map›Paper›PMID 39048823›Full record

ArticleNature2024

TMEFF1 is a neuron-specific restriction factor for herpes simplex virus.

Yao Dai, Manja Idorn, Manutea C Serrero, Xiaoyong Pan, Emil A Thomsen, Ryo Narita, Muyesier Maimaitili, Xiaoqing Qian, Marie B Iversen, Line S Reinert and 19 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Antiviral responses in peripheral and brain neurons.Current opinion in immunology · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Yao Dai *Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Manja Idorn *Department of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-6769-9165
Manutea C SerreroDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-8221-2725
Xiaoyong PanKey Laboratory of System Control and Information Processing (Ministry of Education), Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0001-5010-464X
Emil A ThomsenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-2685-7745
Ryo NaritaDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-2045-2509
Muyesier MaimaitiliDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Xiaoqing QianSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Marie B IversenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Line S ReinertDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Rasmus K FlygaardDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
Muwan ChenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-9676-7756
Xiangning DingDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Bao-Cun ZhangDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-6104-0848
Madalina E Carter-TimofteDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Qing LuKey Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-6956-3333
Zhuofan JiangKey Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Yiye ZhongKey Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Shuhui ZhangKey Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Lintai DaKey Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Jinwei ZhuKey Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Bio-X Institutes, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0001-6657-0143
Mark DenhamDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-5279-5915
Poul NissenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-0948-6628
Trine H MogensenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-1853-9704
Jacob Giehm MikkelsenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Shen-Ying ZhangUniversity of Paris, Imagine Institute, Paris, France.
Jean-Laurent CasanovaUniversity of Paris, Imagine Institute, Paris, France.
Yujia CaiKey Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China. yujia.cai@sjtu.edu.cn.ORCID 0000-0002-2955-7289
Søren R PaludanDepartment of Biomedicine, Aarhus University, Aarhus, Denmark. srp@biomed.au.dk.ORCID 0000-0001-9180-4060

Funding

Danish National Research FoundationDepartment of Molecular Biology and GeneticsEuropean Research CouncilIndependent Research Fund Denmark
6 · The paper itself

Abstract

The brain is highly sensitive to damage caused by infection and inflammation

Indexed as

Antiviral Restriction FactorsBrainHerpes SimplexHerpesvirus 1, HumanMembrane ProteinsNeuronsVirus InternalizationVirus ReplicationAnimalsCell DeathCRISPR-Cas SystemsFemaleHumansInterferon Type IMaleMiceAntiviral Restriction FactorsInterferon Type IMembrane ProteinsNectinsNeoplasm ProteinsNonmuscle Myosin Type IIANonmuscle Myosin Type IIBTMEFF1 protein, humanTmeff1 protein, mouse

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.