ArticleNature2024
Shifts in receptors during submergence of an encephalitic arbovirus.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
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Who cites it
22 citing papers in PubMed.
- Design of a neutralizing and protective pan-encephalitic alphavirus receptor decoy protein.Science translational medicine · 2026Article
- The origins and potential cross-species transmission of paramyxoviruses and other RNA viruses between native snakes and invasive Burmese pythons in the Florida Everglades.Journal of virology · 2026Article
- Informed mutation of western equine encephalitis virus to heparan sulfate binding: Implications for rational design of alphavirus live attenuated vaccines.PLoS pathogens · 2026Article
- Article
- Hidden in Plain Sight: Alphavirus Persistence and Its Potential for Driving Chronic Pathogenesis.Viruses · 2025Review
- Molecular basis of ApoER2-mediated Semliki Forest virus entry.Nature communications · 2025Article
- Structural insights into VLDLR recognition by western equine encephalitis virus.Nature communications · 2025Article
- Western equine encephalitis virus: A comprehensive review of epidemics, transmission, hosts, and strategies for mitigation.Virulence · 2025Review
- LRP8 is an entry receptor for tick-borne encephalitis viruses.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion.Cell reports · 2025Article
- Article
- Determinants of human versus mosquito cell entry by the Chikungunya virus envelope proteins.bioRxiv : the preprint server for biology · 2025Article
- Article
- Review
- Structural basis for engagement of Western Equine Encephalitis Virus with the PCDH10 receptor.Nature communications · 2025Article
- Article
- Article
- Tetraspanins 10 and 15 support Venezuelan equine encephalitis virus replication in astrocytoma cells.Molecular biology of the cell · 2025Article
- Neuropathogenesis of Encephalitic Alphaviruses in Non-Human Primate and Mouse Models of Infection.Pathogens (Basel, Switzerland) · 2025Review
- Review
Corrections and comments
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Authors and funding
28 authors.
Wanyu LiDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5964-1545
Jessica A PlanteWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0002-4768-7458
ChieYu LinDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Himanish BasuDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8236-1157
Jesse S PlungDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1950-7031
Xiaoyi FanDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0009-0002-3181-9994
Joshua M BoeckersDepartment of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Jessica OrosDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0009-0004-9424-7289
Tierra K BuckDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Praju V AnekalDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Wesley A HansonDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-3627-3233
Haley VarnumDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8558-8007
Adrienne WellsDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-3372-5588
Colin J MannDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Laurentia V TjangDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0949-3713
Pan YangDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2431-0252
Rachel A ReynaWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0001-8421-8397
Brooke M MitchellWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.
Divya P ShindeWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.
Jordyn L WalkerWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.
So Yoen ChoiDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Vesna BrusicDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Paula Montero LlopisDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5983-2296
Scott C WeaverWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0001-8016-8556
Hisashi UmemoriDepartment of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-7198-2062
Isaac M ChiuDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0723-4841
Kenneth S PlanteWorld Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0002-7485-3167
Jonathan AbrahamDepartment of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. jonathan_abraham@hms.harvard.edu.ORCID 0000-0002-7937-3920
Funding
Training in the Molecular Biology of Neurodegeneration and Alzheimer's DiseaseT32AG000222 · NIA · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Bruce A YANKNER · 1992 to 2026
$18.5MMedical Scientist Training ProgramT32GM144273 · NIGMS · HARVARD MEDICAL SCHOOL · PI David Shumway Jones, Jacqueline A. Lees · 2022 to 2026
$14.7MMOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6MMOLECULAR BASIS OF VIRAL INFECTIVITYT32AI007245 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Aaron Gregory Schmidt · 1985 to 2026
$11.3MMOLECULAR IMMUNOLOGY AND TUMOR BIOLOGYT32CA009216 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI David Michael Langenau · 1985 to 2026
$10.6MWest African Center for Emerging Infectious DiseasesU01AI151801 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Robert W Cross, Scott C Weaver · 2020 to 2026
$10.1MWorld Reference Center for Emerging Viruses and Arboviruses (WRCEVA)R24AI120942 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2016 to 2024
$8.5MMolecular Codes for the Establishment of Functionally Segregated Dopaminergic CircuitsR01MH125162 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI UMEMORI, HISASHI, WATABE-UCHIDA, MITSUKO · 2021 to 2025
$4.1MStaphylococcus aureus induced itch and neuro-immune signaling in skin infectionsR01AI168005 · NIAID · HARVARD MEDICAL SCHOOL · PI Isaac Ming-Cheng Chiu, ALEXANDER R HORSWILL · 2022 to 2026
$3.7MStructural and functional studies of alphavirus receptorsR01AI182377 · NIAID · HARVARD MEDICAL SCHOOL · PI Jonathan Abraham · 2024 to 2026
$2.2MNCI NIH HHS T32 CA009216NIAID NIH HHS R01 AI168005NIAID NIH HHS R01 AI182377NIAID NIH HHS R24 AI120942NIAID NIH HHS T32 AI007245NIAID NIH HHS U01 AI151801NIA NIH HHS T32 AG000222NIGMS NIH HHS T32 GM008313NIGMS NIH HHS T32 GM144273NIMH NIH HHS R01 MH125162
Abstract
Western equine encephalitis virus (WEEV) is an arthropod-borne virus (arbovirus) that frequently caused major outbreaks of encephalitis in humans and horses in the early twentieth century, but the frequency of outbreaks has since decreased markedly, and strains of this alphavirus isolated in the past two decades are less virulent in mammals than strains isolated in the 1930s and 1940s
Indexed as
Encephalitis Virus, Western EquineHost SpecificityProtocadherinsReceptors, VirusAnimalsBirdsCommunicable Diseases, EmergingEncephalomyelitis, EquineFemaleHumansLDL-Receptor Related ProteinsMaleMiceNeuronsPhenotypeReceptors, LDLLDL-Receptor Related Proteinslow density lipoprotein receptor-related protein 8PCDH10 protein, humanPcdh10 protein, mouseProtocadherinsReceptors, LDLReceptors, VirusViral Envelope ProteinsVLDL receptor
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.