Evidence map›Paper›PMID 39048801›Full record

ArticleNature metabolism2024

Mitochondrial respiration in microglia is essential for response to demyelinating injury but not proliferation.

Joshua S Stoolman, Rogan A Grant, Taylor A Poor, Samuel E Weinberg, Karis B D'Alessandro, Jerica Tan, Jennifer Yuan-Shih Hu, Megan E Zerrer, Walter A Wood, Madeline C Harding and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Neuroinflammation in glaucoma: a myriad of cellular pathways and players.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joshua S StoolmanDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. joshua.stoolman@northwestern.edu.ORCID http://orcid.org/0000-0003-3065-9300
Rogan A GrantDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-0655-0882
Taylor A PoorDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Samuel E WeinbergDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-9532-7051
Karis B D'AlessandroDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jerica TanDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-3495-2600
Jennifer Yuan-Shih HuDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Megan E ZerrerDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Walter A WoodDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Madeline C HardingDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Sahil SoniDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0009-0000-0217-2496
Karen M RidgeDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Paul T SchumackerDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-9591-2034
G R Scott BudingerDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Navdeep S ChandelDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. nav@northwestern.edu.ORCID http://orcid.org/0000-0001-7208-3886

Funding

Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GR Scott Budinger · 2015 to 2026
$26.9M
Northwestern University Allergy Immunology Research Program (NUAIR)T32AI083216 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Stephanie Caroline Eisenbarth, ADAM WILLIAMS · 2010 to 2026
$4.1M
Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Division of Intramural Research of the NIAID) 2T32AI083216-11U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) 2P01AG049665-06
6 · The paper itself

Abstract

Microglia are necessary for central nervous system (CNS) function during development and play roles in ageing, Alzheimer's disease and the response to demyelinating injury

Indexed as

Cell ProliferationDemyelinating DiseasesMicrogliaMitochondriaAnimalsCell RespirationMice

Identifiers

PMID39048801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.