ReviewNature genetics2024
Unlocking plant genetics with telomere-to-telomere genome assemblies.
Review in Nature genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Structural variant detection across sequencing technologies.Nature biotechnology · 2026Article
- Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate-resilient apple breeding.Journal of integrative plant biology · 2026Article
- A near-complete, haplotype-resolved telomere-to-telomere genome assembly of Cannabis sativa reveals complex higher-order repetitive structures.Plant communications · 2026Article
- Revisiting the genome assembly of Lupinus species reveals differential diploidization after a shared whole-genome duplication.G3 (Bethesda, Md.) · 2026Article
- Automatic generation of model sequences for complex regions in assembly graphs with TTT.Cell genomics · 2026Article
- BiTUGA: scalable prevalence-based unitig association testing for binary traits.G3 (Bethesda, Md.) · 2026Article
- Haplotype-resolved genome assembly of a male Dioscorea alata cultivar reveals the structure and evolution of young sex chromosomes.The Plant journal : for cell and molecular biology · 2026Article
- Orchid genome evolution and trait innovation.Journal of integrative plant biology · 2026Review
- T2T-Hub: a central platform for analyzing plant and animal telomere-to-telomere genomes.Nucleic acids research · 2026Article
- Artificial intelligence in plant salt stress research: from predictive models to multi-omics integration.Journal of experimental botany · 2026Review
- Genome Assemblies for Seven Families of Birds From the Global South.Molecular ecology resources · 2026Article
- T2T reference genome assembly provides insights into anthocyanin accumulation in broccoli.Horticulture research · 2026Article
- Building up pangenome analysis block by block.Nature genetics · 2026Article
- Genome-wide identification of MADS-box genes and functional analysis of EgMADS3 in oil palm flower development.BMC plant biology · 2026Article
- Toward telomere-to-telomere genomics in Fabaceae: Unlocking comparative and functional insights into symbiotic nitrogen fixation.Cell genomics · 2026Review
- Nanopore Data-Driven Near-T2T Genome Assembly ofPlants (Basel, Switzerland) · 2026Article
- Genomic insights into alpine plant adaptation.Plant diversity · 2026Review
- Three Near telomere-to-telomere Genomes for Gardenia jasminoides.Scientific data · 2026Article
- Telomere-to-telomere genome assembly and comprehensive mutation library facilitate bitter gourd breeding and functional genomics research.Plant communications · 2026Article
- A haplotype-resolved, chromosome-scale genome assembly for the southern live oak, Quercus virginiana.G3 (Bethesda, Md.) · 2026Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contiguous genome sequence assemblies will help us to realize the full potential of crop translational genomics. Recent advances in sequencing technologies, especially long-read sequencing strategies, have made it possible to construct gapless telomere-to-telomere (T2T) assemblies, thus offering novel insights into genome organization and function. Plant genomes pose unique challenges, such as a continuum of ancient to recent polyploidy and abundant highly similar and long repetitive elements. Owing to progress in sequencing approaches, for most crop plants, chromosome-scale reference genome assemblies are available, but T2T assembly construction remains challenging. Here we describe methods for haplotype-resolved, gapless T2T assembly construction in plants, including various crop species. We outline the impact of T2T assemblies in elucidating the roles of repetitive elements in gene regulation, as well as in pangenomics, functional genomics, genome-assisted breeding and targeted genome manipulation. In conjunction with sequence-enriched germplasm repositories, T2T assemblies thus hold great promise for basic and applied plant sciences.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.