Evidence map›Paper›PMID 39048742›Full record

ArticleEuropean radiology2025

T2* cartilage mapping in early axial spondyloarthritis: diagnostic accuracy and correlation with clinical characteristics, sacroiliitis MRI scorings, and diffusion metrics.

Hongjie Huang, Feifei Zhuang, Xi Liu, Keyi Wu, Feng Wang, Xiance Zhao, Yuyang Zhang, Dairong Cao

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Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Hongjie Huang *Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Feifei Zhuang *Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Xi LiuDepartment of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Keyi WuDepartment of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Feng WangDepartment of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Xiance ZhaoPhilips Healthcare, Shanghai, China.
Yuyang ZhangDepartment of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. zhangyuyang001@126.com.
Dairong CaoDepartment of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. dairongcao@163.com.ORCID http://orcid.org/0000-0002-0051-3143

Funding

Joint Funds for the Innovation of Science and Technology, Fujian Province 2021Y9124National Natural Science Foundation of China 82202087
6 · The paper itself

Abstract

purposeTo determine the performance of T2* cartilage mapping in diagnosing and assessing disease activity in early axial spondyloarthritis (axSpA), and to investigate the interaction of cartilage damage with clinical characteristics, sacroiliitis MRI scorings, and diffusion metrics. MATERIALS AND

methodsThis prospective study included 83 axSpA patients and 37 no-axSpA patients. Clinical characteristics, the Assessment of SpondyloArthritis International Society-defined active sacroiliitis on MRI, and T2*

resultsAxSpA patients had significantly higher T2*

conclusionT2* values may be a promising biomarker for diagnosing and differentiating disease activity in early axSpA. Both acute and chronic sacroiliitis influence cartilage properties. CLINICAL RELEVANCE STATEMENT: Sacroiliac joint cartilage abnormalities can be quantified with T2* relaxation time and allow better characterization of early axSpA. KEY POINTS: T2* mapping may have value in evaluating axSpA. The combination of T2* values and active sacroiliitis on MRI enhances diagnostic performance for axSpA. Abnormalities measured with T2* values correlate with disease activity, acute sacroiliitis, and degree of structural damage.

Indexed as

Axial SpondyloarthritisCartilage, ArticularMagnetic Resonance ImagingSacroiliitisAdultFemaleHumansMaleMiddle AgedProspective StudiesReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexAxial spondyloarthritisCartilageDiffusion magnetic resonance imagingSacroiliitis

Identifiers

PMID39048742

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