Evidence map›Paper›PMID 39048738›Full record

ArticleSurgical endoscopy2024

Long-term outcome of regional cooperation pathway after endoscopic submucosal dissection for early detection of new gastric cancer.

Asuka Ishigaki, Yoshiyasu Kitagawa, Kaori Yoshida, Yoshihisa Takeuchi, Masumi Minowa, Kunishige Koga, Mamoru Tokunaga, Osamu Sugita, Kazuya Yamaguchi, Akinori Koide and 12 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Asuka IshigakiEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan. aishigaki@chiba-cc.jp.ORCID 0009-0007-4696-0305
Yoshiyasu KitagawaEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.
Kaori YoshidaRegional Medical Liaison Office, Chiba Cancer Center, Chiba, Japan.
Yoshihisa TakeuchiEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.
Masumi MinowaEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.
Kunishige KogaEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.
Mamoru TokunagaEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.
Osamu SugitaEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.
Kazuya YamaguchiChiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
Akinori KoideKoide Internal Medical Clinic, Chiba, Japan.
Shigemi KodaOyumino Clinic, Chiba, Japan.
Hidehiko KoyamaKamatori Station Clinic, Chiba, Japan.
Fumitaka NagashimaNagashima Clinic, Chiba, Japan.
Takeo OdakaOdaka Medical and Gastrointestinal Clinic, Chiba, Japan.
Kiyoshi FurukawaFurukawa Clinic, Chiba, Japan.
Yoichi ToyamaIchihara Medical Cure, Chiba, Japan.
Yoshio KitsukawaDepartment of Gastroenterology, Chiba Aoba Municipal Hospital, Chiba, Japan.
Hirofumi SaitoDepartment of Gastroenterology, Chiba Kaihin Municipal Hospital, Chiba, Japan.
Yoshihiro NabeyaDivision of Esophago-Gastrointestinal Surgery, Chiba Cancer Center, Chiba, Japan.
Tsukasa YonemotoRegional Medical Liaison Office, Chiba Cancer Center, Chiba, Japan.
Taketo YamaguchiDepartment of Gastroenterology, Funabashi Central Hospital, Chiba, Japan.
Takuto SuzukiEndoscopy Division, Chiba Cancer Center, 666-2 Nitonacho, Chuo, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe Cancer Control Act requires the maintenance of regional cooperation pathways (RCP) for cancer treatment. In 2008, we started RCP for early detection of new gastric cancer after endoscopic submucosal dissection (ESD). In gastric cancer treatment, RCP after surgical resection had been widely used, but little is known about RCP after ESD. This study aimed to evaluate the effectiveness of RCP after ESD.

methodsThis study included 465 patients on whom our RCP was implemented from 2008 to 2018. A regional family physician performed surveillance endoscopy at 3 months and 1 year after ESD and annually thereafter. We retrospectively evaluated the cumulative incidence and treatment outcomes of new gastric cancer and compared them with previous reports.

resultsDuring a median follow-up period of 70.5 months (3-120 months), 58 patients developed new gastric cancers, and metachronous gastric cancer was detected in 55 patients more than 1 year after ESD. The 5-year cumulative incidence rate was 9.8%. Three patients did not want treatment. Among the remaining 55 patients, the initial treatment was ESD in 51 and surgical resection in 4. Eventually, 50 patients (48 in the ESD group and 2 in the surgical resection group) fulfilled the pathologic criteria for curative ESD. There were no deaths due to gastric cancer.

conclusionOur study was the first to reveal the incidence of new gastric cancer after ESD using RCP. Most lesions were cured with ESD, and no patients died of gastric cancer. Therefore, we consider RCPs to be an option for surveillance after ESD.

Indexed as

Early Detection of CancerEndoscopic Mucosal ResectionStomach NeoplasmsAgedAged, 80 and overFemaleFollow-Up StudiesGastroscopyHumansIncidenceMaleMiddle AgedRetrospective StudiesTreatment OutcomeEndoscopic submucosal dissectionMetachronous gastric cancerRegional cooperation pathway

Identifiers

PMID39048738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.