ArticleThe Biochemical journal1985
Structural variations in actins. Biochemical and immunological tools for probing the structure of rabbit skeletal-muscle and bovine aortic actins.
Article in The Biochemical journal, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Structural and functional variations in skeletal-muscle and scallop muscle actins.The Biochemical journal · 1988Article
- Anti-actin antibodies. An immunological approach to the myosin-actin and the tropomyosin-actin interfaces.The Biochemical journal · 1987Article
- Actin antibodies. Preparation and characterization of antibodies specific for smooth-muscle actin isoforms.The Biochemical journal · 1987Article
- A novel isoform of cytoplasmic actin that binds poly-L-proline.The Biochemical journal · 1986Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural differences between skeletal-muscle and aortic actins were studied by using biochemical and immunological approaches. By using proteinase digestion we found that three regions of actin show structural differences: (a) in the C-terminal part, (b) the region around residue 227 and (c) the region around residue 167. By using antibodies specific to particular actin conformations we can discriminate between monomeric and filamentous forms of the two actins. Our results show that the minor sequence variations of the N- and C-terminal regions induce structural change in these regions, but also some long-range structural variations in other regions.
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