Evidence map›Paper›PMID 39047258›Full record

Observational studyPain2025

Prevalence, pain trajectories, and presurgical predictors for chronic postsurgical pain in a pediatric sample in Spain with a 24-month follow-up.

Guillermo Ceniza-Bordallo, Andrés Gómez Fraile, Patricia Martín-Casas, Jennifer A Rabbitts, Rui Li, Tonya M Palermo, Ibai López-de-Uralde-Villanueva

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04735211 (Risk Factors to Develop Chronic Postsurgical Pediatric Pain), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04735211 unknown statusnot on this map

Risk Factors to Develop Chronic Postsurgical Pediatric Pain: An Observational Study

TypeobservationalSponsorGuillermo Ceniza BordalloRan2020 to 2021Enrolled260ConditionsChronic Postoperative Pain, Pediatric ALLArmsSurgery
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guillermo Ceniza-BordalloDoctoral Program in Healthcare, Faculty of Nursing, Physiotherapy and Podiatry, University Complutense of Madrid, Madrid, Spain.
Andrés Gómez FraileHead of Service, Surgery and Urology Pediatric Unit, University Hospital 12 Octubre of Madrid, Madrid, Spain.
Patricia Martín-CasasDepartment of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, Physiotherapy, and Podiatry, University Complutense of Madrid, Madrid, Spain.ORCID 0000-0002-5889-1841
Jennifer A RabbittsDepartment of Anesthesiology, Perioperative, and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.
Rui LiCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, United States.
Tonya M PalermoCenter for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, United States.
Ibai López-de-Uralde-VillanuevaDepartment of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursing, Physiotherapy, and Podiatry, University Complutense of Madrid, Madrid, Spain.ORCID 0000-0001-7474-5257

Funding

Preventing the Transition from Acute to Chronic Musculoskeletal Pain in Adolescents after Surgery: The Role of SleepK24AR080786 · NIAMS · STANFORD UNIVERSITY · PI Jennifer Rabbitts · 2023 to 2026
$712k
NIAMS NIH HHS Award K24AR080786NIAMS NIH HHS K24 AR080786Universidad Complutense de Madrid CT58/21-CT59/21
6 · The paper itself

Abstract

abstractPediatric chronic pain, particularly chronic postsurgical pain (CPSP), poses a significant public health challenge, impacting 20% of pediatric populations. While several presurgical predictors have been identified, there is a scarcity of data on long-term outcomes, especially beyond 1 to 2 years postsurgery. Previous research primarily focuses on North American children, creating gaps in understanding CPSP outcomes in diverse health systems, such as in Spain. This study, registered as NCT04735211, investigates CPSP in 159 children and adolescents (mean age = 12.4 years, 37.1% girls, retention rate = 65%) undergoing various surgeries in Spain. The objectives include examining CPSP prevalence (Numerical Rating Scale ≥ 4) at 3, 6, 12, and 24 months, exploring postsurgical pain trajectories through group-based trajectory modeling, and identifying potential presurgical predictors for CPSP (pain intensity, pain catastrophizing, pain anxiety, fear of pain, kinesiophobia, health-related quality of life, pain interference, and physical activity), using multiple logistic regressions. Results show a CPSP prevalence of 41% at 3 months, decreasing to 14% at 24 months. Presurgical factors including pain intensity (adjusted odds ratio [aOR] = 1.25, 95% confidence interval [CI] = 1.02-1.53), pain catastrophizing (aOR = 1.06, 95% CI = 1.00-1.13), and pain anxiety (aOR = 1.06, 95% CI = 1.02-1.11) were associated with CPSP at 3 months. Group-based trajectory modeling revealed 3 postsurgical pain trajectories: Low Pain with Rapid Recovery Group (30.2%), Moderate Pain with Recovery Group (53.5%), and High Pain with Slow Recovery Group (16.3%), with group differences in presurgical predictors, excluding physical activity. This study contributes valuable insights into CPSP, emphasizing the need for long-term follow-up. The findings could inform the implementation of preventive programs for CPSP into diverse health systems.

Indexed as

Chronic PainPostoperative PainAdolescentCatastrophizationChildFemaleFollow-Up StudiesHumansMalePain MeasurementPrevalenceQuality of LifeSpain

Identifiers

PMID39047258
PMCPMC11856900

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.