Evidence map›Paper›PMID 39047091›Full record

ArticleScience advances2024

Single-cell RNA-seq reveals distinct metabolic "microniches" and close host-symbiont interactions in deep-sea chemosynthetic tubeworm.

Hao Wang, Hongxiu Xiao, Buhan Feng, Yi Lan, Cheuk Wang Fung, Huan Zhang, Guoyong Yan, Chao Lian, Zhaoshan Zhong, Jing Li and 4 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hao WangInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.ORCID 0000-0002-9435-5501
Hongxiu XiaoDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.ORCID 0000-0003-2052-5261
Buhan FengDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.
Yi LanSouthern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Nansha, Guangzhou, China.ORCID 0000-0001-5501-1063
Cheuk Wang FungDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.ORCID 0000-0003-4485-8407
Huan ZhangInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.ORCID 0000-0001-7269-8004
Guoyong YanSouthern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Nansha, Guangzhou, China.ORCID 0000-0002-6603-6351
Chao LianInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.ORCID 0009-0009-5696-737X
Zhaoshan ZhongInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.ORCID 0000-0003-1643-5407
Jing LiInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.
Minxiao WangInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.ORCID 0000-0002-6567-3295
Angela Ruohao WuDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.ORCID 0000-0002-3531-4830
Chaolun LiInstitute of Oceanology, Chinese Academy of Science, Qingdao, China.ORCID 0000-0003-1890-0587
Pei-Yuan QianDivision of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.ORCID 0000-0003-4074-9078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vestimentiferan tubeworms that thrive in deep-sea chemosynthetic ecosystems rely on a single species of sulfide-oxidizing gammaproteobacterial endosymbionts housed in a specialized symbiotic organ called trophosome as their primary carbon source. While this simple symbiosis is remarkably productive, the host-symbiont molecular interactions remain unelucidated. Here, we applied an approach for deep-sea in situ single-cell fixation in a cold-seep tubeworm,

Indexed as

PolychaetaRNA-SeqSingle-Cell AnalysisSymbiosisAnimalsGammaproteobacteriaSingle-Cell Gene Expression Analysis

Identifiers

PMID39047091
PMCPMC11268408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.