Evidence map›Paper›PMID 39047090›Full record

ArticleScience advances2024

Astrocytes control quiescent NSC reactivation via GPCR signaling-mediated F-actin remodeling.

Kun-Yang Lin, Mahekta R Gujar, Jiaen Lin, Wei Yung Ding, Jiawen Huang, Yang Gao, Ye Sing Tan, Xiang Teng, Low Siok Lan Christine, Pakorn Kanchanawong and 2 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Regulating glial morphogenesis: insights fromFrontiers in cell and developmental biology · 2026
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kun-Yang LinNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0002-6197-3995
Mahekta R GujarNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0001-8702-4352
Jiaen LinNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0001-7229-4456
Wei Yung DingNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
Jiawen HuangNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0002-5340-2770
Yang GaoNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0001-6357-7470
Ye Sing TanNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0002-4840-1853
Xiang TengMechanobiology Institute, Level 5, T-lab Building, 5A Engineering Drive 1, Singapore, 117411, Singapore.
Low Siok Lan ChristineMechanobiology Institute, Level 5, T-lab Building, 5A Engineering Drive 1, Singapore, 117411, Singapore.
Pakorn KanchanawongMechanobiology Institute, Level 5, T-lab Building, 5A Engineering Drive 1, Singapore, 117411, Singapore.ORCID 0000-0001-8765-3861
Yusuke ToyamaMechanobiology Institute, Level 5, T-lab Building, 5A Engineering Drive 1, Singapore, 117411, Singapore.ORCID 0000-0003-3230-1062
Hongyan WangNeuroscience and Behavioral Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0003-4623-1878

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transitioning of neural stem cells (NSCs) between quiescent and proliferative states is fundamental for brain development and homeostasis. Defects in NSC reactivation are associated with neurodevelopmental disorders.

Indexed as

ActinsAstrocytesDrosophila ProteinsNeural Stem CellsReceptors, G-Protein-CoupledSignal TransductionActin CytoskeletonAnimalsDrosophila melanogasterrho GTP-Binding ProteinsActinsDrosophila ProteinsReceptors, G-Protein-CoupledRho1 protein, Drosophilarho GTP-Binding Proteins

Identifiers

PMID39047090
PMCPMC11268418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.