Evidence map›Paper›PMID 39046669›Full record

ArticleOphthalmology and therapy2024

Efficacy and Safety of Preoperative Prophylaxis in Cataract Surgery with Combined Topical Antiseptics: A Microbiological Study.

Rocco Luigi Modugno, Adriano Fasolo, Davide Camposampiero, Diego Ponzin, Marco Tavolato

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rocco Luigi ModugnoDepartment of Ophthalmology, Camposampiero Hospital, Padua, Italy. roccoluigi.modugno@aulss6.veneto.it.ORCID http://orcid.org/0000-0002-6841-1266
Adriano FasoloFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venice, Italy.ORCID http://orcid.org/0000-0003-2202-7477
Davide CamposampieroFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venice, Italy.ORCID http://orcid.org/0000-0002-5459-0275
Diego PonzinFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venice, Italy.ORCID http://orcid.org/0000-0002-6038-3977
Marco TavolatoDepartment of Ophthalmology, Camposampiero Hospital, Padua, Italy.ORCID http://orcid.org/0009-0003-9608-8819

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo evaluate the antimicrobial efficacy of an ophthalmic formulation containing hexamidine diisethionate (HD) 0.05%, polyhexamethylene biguanide (PHMB) 0.0001%, and edetate disodium (EDTA) 0.01% (Keratosept

methodsPatients were enrolled consecutively. Each patient applied two drops of Keratosept

resultsConjunctival swabs of 32 patients (n = 128) were examined. Six patients were excluded from the efficacy analysis because of microbial load < 50 CFU/mL at T0 in the study eye. No difference between study and control eyes was observed at T0 (p = 0.40). Compared with T0, 20 (76.9%) study eyes and 10 (38.5%) control eyes showed a ≥ 1 log reduction of the microbial load at T1, with a significant difference between groups (p = 0.005). Keratosept

conclusionsThis study showed that the low-dose combination of antiseptic agents in the Keratosept

Indexed as

AntisepticsCataract surgeryEDTAHexamidineOcular surfacePolyhexamethylene biguanide

Identifiers

PMID39046669
PMCPMC11341795

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.