Evidence map›Paper›PMID 39046613›Full record

Observational studyAIDS and behavior2024

Condom Failure Among HIV-Negative Men in Serodiscordant Relationships in Australia, Brazil, and Thailand.

James Gray, Garrett Prestage, Fengyi Jin, Nittaya Phanuphak, Ruth K Friedman, Christopher K Fairley, David J Templeton, Iryna Zablotska-Manos, Jennifer Hoy, Mark Bloch and 5 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

James GrayKirby Institute, UNSW Sydney, Sydney, Australia. jgray@kirby.unsw.edu.au.ORCID http://orcid.org/0000-0001-7090-293X
Garrett PrestageKirby Institute, UNSW Sydney, Sydney, Australia.
Fengyi JinKirby Institute, UNSW Sydney, Sydney, Australia.
Nittaya PhanuphakInstitute of HIV Research and Innovation, Bangkok, Thailand.
Ruth K FriedmanInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Christopher K FairleyMelbourne Sexual Health Centre, Melbourne, Australia.
David J TempletonKirby Institute, UNSW Sydney, Sydney, Australia.
Iryna Zablotska-ManosWestmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Jennifer HoyDepartment of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, Australia.
Mark BlochKirby Institute, UNSW Sydney, Sydney, Australia.
David BakerEast Sydney Doctors, Sydney, Australia.
Graham BrownCentre for Social Impact, UNSW Sydney, Sydney, Australia.
Andrew GrulichKirby Institute, UNSW Sydney, Sydney, Australia.
Benjamin BavintonKirby Institute, UNSW Sydney, Sydney, Australia.
Opposites Attract study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Condoms continue to be used by many gay, bisexual, and other men who have sex with men (GBM) to reduce the risk of HIV transmission. However this is impacted by condom failure events, defined here as condom breakage and slippage. In a prospective, observational cohort study of 343 HIV serodiscordant male couples recruited through high HIV caseload clinics and hospitals between 2012 and 2016 in Australia, Brazil, and Thailand, condom failure rates and associated factors were analysed, including with the study partner versus other sexual partners. There were 717 reported instances of condom failure from an estimated total of 25,831 sex acts with condoms, from over 588.4 participant years of follow up. Of the HIV-negative partners (n = 343) in the study, more than a third (n = 117, 36.7%) reported at least one instance of condom failure with any partner type during study follow-up. Condom failure with their study partner was reported by 91/343 (26.5%) HIV-negative partners, compared with 43/343 (12.5%) who reported condom failure with other partners. In total, there were 86 events where the HIV-negative partner experienced ano-receptive condom failure with ejaculation, representing 12.0% of all failure events. In multivariable analysis, compared to Australia, HIV-negative men in Brazil reported a higher incidence risk rate of condom failure (IRR = 1.64, 95%CI 1.01-2.68, p = 0.046) and HIV-negative men who reported anal sex with other partners reported an increased risk of condom failure compared with men who only had sex with their study partner (IRR = 1.89, 95%CI 1.08-3.33, p = 0.025). Although at least one event of condom failure was reported by a significant proportion of participants, overall condom failure events represented a small proportion of the total condom protected sex acts.

Indexed as

CondomsHIV InfectionsHomosexuality, MaleSexual PartnersAdultAustraliaBrazilHIV SeronegativityHumansMaleMiddle AgedProspective StudiesSafe SexSexual BehaviorThailandCondomsGay menHIVMen who have sex with menRelationshipsSexual risk behaviour

Identifiers

PMID39046613
PMCPMC11471711

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.