Evidence map›Paper›PMID 39046610›Full record

ArticleAIDS and behavior2024

Disrupting the Path from Depression to Loneliness: Multilevel Resilience among Older Sexual Minority Men with and without HIV.

Maria De Jesus, Deanna Ware, Steven Meanley, Mark Brennan-Ing, Chukwuemeka N Okafor, Steve Shoptaw, Sabina Haberlen, Valentina Stosor, M Reuel Friedman, Michael Plankey

Abstract read
In one paragraph

Article in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria De JesusDepartment of Environment, Development and Health, School of International Service and Center on Health, Risk, and Society, American University, 4400 Massachusetts Avenue NW, Washington, DC, 20016, USA. dejesus@American.edu.ORCID http://orcid.org/0000-0002-6757-2746
Deanna WareDepartment of Medicine, Georgetown University Medical Center, Washington, DC, USA.
Steven MeanleyDepartment of Family and Community Health, University of Pennsylvania School of Nursing, Philadelphia, USA.
Mark Brennan-IngDepartment of Geriatrics, Brookdale Center for Healthy Aging, City University of New York, New York City, NY, USA.
Chukwuemeka N OkaforDepartment of Public Health, Robbins College of Health and Human Sciences, Baylor University, Waco, USA.
Steve ShoptawDepartment of Family Medicine, University of California, Los Angeles, CA, USA.
Sabina HaberlenDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins, Baltimore, MD, USA.
Valentina StosorDepartment of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
M Reuel Friedman *Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Michael Plankey *Department of Medicine, Division of General Internal Medicine, Georgetown University, Washington, DC, USA.

Funding

Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center - Admin Supplement: Vision and dual sensory loss in HIV-infected older adultsU01HL146201 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Joseph B. Margolick · 2019 to 2026
$33.7M
Sex differences in the role of multi-omics in HIV-associated carotid artery atherosclerosisU01HL146204 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI David B. Hanna, Anjali Sharma · 2019 to 2026
$33.2M
University of Pittsburgh MWCCS Clinical Research SiteU01HL146208 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Bernard Jonas C Macatangay, CHARLES R RINALDO · 2019 to 2026
$32.2M
Northwestern CORE Clinical Research Site: Trans-omics for HIV/AIDS ResearchU01HL146240 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Frank J Palella, Valentina Stosor · 2019 to 2026
$31.5M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube · 2013 to 2026
$23.5M
Surviving the HIV Epidemic (S/HE) in metropolitan Washington DC - Advancing knowledge through cohort studiesU01HL146205 · NHLBI · GEORGETOWN UNIVERSITY · PI SEBLE G KASSAYE, DANIEL J MERENSTEIN · 2019 to 2026
$23.5M
Understanding Patterns of Healthy Aging among Men Who Have Sex with MenR01MD010680 · NIMHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRIEDMAN, MACKEY R, PLANKEY, MICHAEL W · 2015 to 2019
$2.9M
NHLBI NIH HHS U01 HL146201NHLBI NIH HHS U01 HL146204NHLBI NIH HHS U01 HL146205NHLBI NIH HHS U01 HL146208NHLBI NIH HHS U01 HL146240NIMHD NIH HHS R01 MD010680NIMH NIH HHS P30 MH097488
6 · The paper itself

Abstract

Existing studies examining resilience among sexual minority men (SMM) have been limited by only analyzing 1 level of resilience. We therefore investigated the impact of multiple levels of resilience on the bidirectional relationship between loneliness and depression symptoms among older SMM. Loneliness, depression symptoms, and multilevel resilience scores were collected across 3 time points (October 2016 to March 2017 [T1]; October 2017 to March 2018 [T2]; and October 2018 to March 2019 [T3]) among 1,264 SMM aged 40 years and older living with and without HIV. Longitudinal mediation models were used to test the mediating effect of the multilevel resilience factors at T2 on the bidirectional relationship between loneliness and depression symptoms, adjusting for sociodemographic covariates. The multilevel resilience factors were negatively associated with loneliness and depression symptoms at T1. The individual-level global resilience factor was associated with decreased odds of depression symptoms (odds ratio [OR] = 0.50; 95% CI, 0.32-0.78), while the interpersonal-level relationship confidence (OR = 0.43; 95% CI, 0.24-0.77) and reliability (OR = 0.36; 95% CI, 0.15-0.84) factors were associated with decreased odds of loneliness at T3. The total effect of loneliness at T1 on depressive symptoms at T3 was β = 0.20 (95% CI, 0.11-0.28) and was reduced to β = 0.08 (95% CI, -0.04 to 0.20) after the inclusion of the multilevel resilience factors. The total effect of depressive symptoms at T1 on loneliness at T3 was similar (β = 0.21; 95% CI, 0.13-0.28) with the direct effect of β = 0.01 (95% CI, -0.08 to 0.11) after the inclusion of the multilevel resilience factors. Regarding specific indirect effects, individual-level global resilience (depression symptoms at T3 only) as well as the interpersonal-level relationship reliability and confidence (loneliness at T3 model only) factors were statistically significant. Multilevel resilience factors mediated the bidirectional relationship between loneliness and depression symptoms. Mental health interventions should consider implementing resilience-informed strategies that mitigate depression symptoms and loneliness among older SMM.

Indexed as

DepressionHIV InfectionsLonelinessResilience, PsychologicalSexual and Gender MinoritiesAdultAgedHomosexuality, MaleHumansLongitudinal StudiesMaleMiddle AgedAgingDepressionHIV/AIDSLonelinessResilienceSexual minority men

Identifiers

PMID39046610
PMCPMC11471709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.